P0622

PET-cGMP

≥98% (HPLC), solid

• Synonym(e): β-Phenyl-1,N²-ethenoguanosine 3′,5′-monophosphate sodium salt
• Empirische Formel (Hill-System): C₁₈H₁₅N₅O₇PNa
• CAS-Nummer: 78080-27-0
• Molekulargewicht: 467.30
• MDL-Nummer: MFCD04118064
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24724570
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: solid
• Verpackung: pkg of 10 μmol
• Farbe: white
• Löslichkeit: H₂O: ~10 mmol
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• SMILES String: [Na+].O[C@@H]1[C@@H]2OP([O-])(=O)OC[C@H]2O[C@H]1n3cnc4C(=O)N5C=C(NC5=Nc34)c6ccccc6
• InChI: 1S/C18H16N5O7P.Na/c24-13-14-11(7-28-31(26,27)30-14)29-17(13)23-8-19-12-15(23)21-18-20-10(6-22(18)16(12)25)9-4-2-1-3-5-9;/h1-6,8,11,13-14,17,24H,7H2,(H,20,21)(H,26,27);/q;+1/p-1/t11-,13-,14-,17-;/m1./s1
• InChIKey: IGIOCJJIGJLGKR-TZNCIMHNSA-M

Beschreibung

Biochem./physiol. Wirkung

cGMP-dependent protein kinase (PKG I and PKG II) activator. Potent membrane permeant activator of both isozymes I α and I β of cGMP-dependent protein kinase. Common stimulators such as 8-Br-cGMP or 8-pCPT-cGMP mainly activate kinase subtype Iα.

Leistungsmerkmale und Vorteile

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)