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G8790

Sigma-Aldrich

Glycin

≥98.5%, suitable for cell culture, non-animal source, meets EP, JP, USP testing specifications

Synonym(e):

Aminoessigsäure, Aminoethansäure, Glycokoll

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About This Item

Lineare Formel:
NH2CH2COOH
CAS-Nummer:
56-40-6
Molekulargewicht:
75.07
Beilstein:
635782
EG-Nummer:
200-272-2
MDL-Nummer:
MFCD00008131
UNSPSC-Code:
12352209
eCl@ss:
32160406
PubChem Substanz-ID:
24895353
NACRES:
NA.26
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Produktbezeichnung

Glycin, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%

Biologische Quelle

non-animal source

Qualitätsniveau

300

Agentur

meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

Assay

≥98.5%

Form

powder

Qualität

meets EP, JP, USP testing specifications

Methode(n)

cell culture | mammalian: suitable

Verunreinigungen

endotoxin, tested

Farbe

white

pH-Wert

5.9-6.4

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp (Schmelzpunkt)

240 °C (dec.) (lit.)

Löslichkeit

H2O: 100 mg/mL

SMILES String

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChIKey

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Angaben zum Gen

rat ... Grin2a(24409)

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Anwendung

Amino acid for use in cell culture media development applications and existing media formulations.

Biochem./physiol. Wirkung

Hemmender Neurotransmitter im Rückenmark; allosterischer Regulator von NMDA-Rezeptoren.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
0000411071
0000411070
0000411071
0000411070
0000411069

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Glycin tested according to Ph. Eur.

Sigma-Aldrich

50058

Glycin

Pyridoxin -hydrochlorid BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

Sigma-Aldrich

P6280

Pyridoxin -hydrochlorid

Glycin ACS reagent, ≥98.5%

Sigma-Aldrich

410225

Glycin

Glycin United States Pharmacopeia (USP) Reference Standard

USP

1295800

Glycin

Glycin European Pharmacopoeia (EP) Reference Standard

G0450000

Glycin

Glycin suitable for electrophoresis, ≥99%

Sigma-Aldrich

G8898

Glycin

L-Glutaminsäure from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%

Sigma-Aldrich

G8415

L-Glutaminsäure

Richard A Felix et al.
Brain structure & function, 220(5), 2639-2652 (2014-06-30)
The mammalian superior paraolivary nucleus (SPON) is a major source of GABAergic inhibition to neurons in the inferior colliculus (IC), a well-studied midbrain nucleus that is the site of convergence and integration for the majority ascending auditory pathways en route
Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
Zoé Husson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(28), 9418-9431 (2014-07-11)
The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory
Bethany L Johnson-Kerner et al.
Human molecular genetics, 24(5), 1420-1431 (2014-11-16)
Giant axonal neuropathy (GAN) is a progressive neurodegenerative disease caused by autosomal recessive mutations in the GAN gene resulting in a loss of a ubiquitously expressed protein, gigaxonin. Gene replacement therapy is a promising strategy for treatment of the disease;
Dmitrij A Lisak et al.
Biochimica et biophysica acta, 1853(9), 2104-2114 (2015-03-15)
Bax inhibitor-1 (BI-1) is an evolutionarily conserved pH-dependent Ca²⁺ leak channel in the endoplasmic reticulum and the founding member of a family of six highly hydrophobic mammalian proteins named transmembrane BAX inhibitor motif containing (TMBIM) 1-6 with BI-1 being TMBIM6.
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Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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