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G5422

Sigma-Aldrich

Glycerin-2-phosphat Dinatriumsalz Hydrat

≤1.0 mol % L-α-isomer

Synonym(e):

β-Glycerophosphat Dinatriumsalz Hydrat, BGP

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100 G
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25 G
CHF 77.70
100 G
CHF 168.00
500 G
CHF 724.00

About This Item

Lineare Formel:
(HOCH2)2CHOP(O)(ONa)2 · xH2O
CAS-Nummer:
154804-51-0
Molekulargewicht:
216.04 (anhydrous basis)
EG-Nummer:
212-464-3
MDL-Nummer:
MFCD00149082
UNSPSC-Code:
12352201
PubChem Substanz-ID:
329799941
NACRES:
NA.25

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Biologische Quelle

synthetic

Qualitätsniveau

300

Form

powder

Verunreinigungen

≤0.1% Inorganic phosphorus
≤1.0 mol % L-α-isomer

mp (Schmelzpunkt)

102-104 °C (lit.)

Löslichkeit

water: 50 mg/mL, clear, colorless

SMILES String

O.[Na+].[Na+].OCC(CO)OP([O-])([O-])=O

InChI

1S/C3H9O6P.2Na.H2O/c4-1-3(2-5)9-10(6,7)8;;;/h3-5H,1-2H2,(H2,6,7,8);;;1H2/q;2*+1;/p-2

InChIKey

ROPZSVKNEIIIDE-UHFFFAOYSA-L

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Anwendung

β-Glycerophosphat ist ein klassischer Serin-Threonin-Phosphatase-Inhibitor, der in Kinase-Reaktionspuffern verwendet wird. BGP wird häufig in Kombination mit anderen Phosphatase-/Protease-Inhibitoren zur Breitbandhemmung eingesetzt. Es fungiert als Spender von organischem Phosphat und wird in Kulturmedien für die Differenzierung zwischen mesenchymalen Stammzellen und osteoblastenähnlichen Zellen verwendet. Darüber hinaus wird BGP als Puffer für M17-Medium bei Lactococcus-Kulturen für die rekombinante Proteinexpression verwendet.
Startet die Differenzierung von Stammzellen aus dem Knochenmark, die in ein für die Gewebezüchtung entwickeltes natürliches Kollagen/Chitosan-Gel eingebettet sind.
β-glycerophosphate is used in homegenization solutions for muscles extracts following fixation. [1]

Qualität

Low inorganic phosphate content. Mixtures of α- and β-glycerophosphate have historically been used in microbiological media but high levels of inorganic (free) phosphate has been associated with the irregular growth of bacteria and unwanted precipitates.[2]

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H319

Gefahreneinstufungen

Eye Irrit. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
0000395344
0000395344
0000421829
0000421830
0000421829

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Yang An et al.
Biochemical and biophysical research communications, 516(2), 551-557 (2019-06-27)
Developing methods for regenerating bones and uncovering the molecular mechanism underlying bone formation have great significance to human health. In the last decade, people have been using adipose-derived stem cells (ADSCs), that are capable of multilineage differentiation, to reconstruct defected
Morten Donsmark et al.
The Journal of physiology, 550(Pt 3), 845-854 (2003-06-10)
Intramuscular triacylglycerol is an important energy store and is also related to insulin resistance. The mobilization of fatty acids from this pool is probably regulated by hormone-sensitive lipase (HSL), which has recently been shown to exist in muscle and to
J Douglas et al.
The Journal of applied bacteriology, 56(2), 321-326 (1984-04-01)
An easily prepared medium, originally designed for the cultivation of lactic phages, has been found to have much wider application. Experience in its use over a ten year period with a range of physiologically diverse bacteria, for teaching and research
Chien-Ying Wang et al.
Journal of tissue engineering and regenerative medicine, 14(10), 1438-1448 (2020-08-09)
Peripheral arterial disease (PAD) affects more than 200 million people worldwide. Recent studies suggest that oxidative stress-related inflammation can lead to the initiation and progression of PAD. Ferulic acid (FA) is a natural phenolic compound and has been proven to
Lucas R Brun et al.
SpringerPlus, 3, 676-676 (2014-12-19)
The aim of this study was to evaluate the effect of strontium ranelate (SrR) on bone mineral density (BMD) and bone turnover markers after 1 year of treatment. Additionally, the effect of SrR in bisphosphonate-naïve patients (BP-naïve) compared to patients previously
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Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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