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G4256
Galactose-1-phosphate Uridyltransferase from galactose-adapted yeast
Type IV, lyophilized powder, 20-60 units/mg protein (modified Warburg-Christian)
Synonym(e):
GALT, UDP glucose:α-D-galactose-1-phosphate uridyltransferase
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20 UNITS
CHF 842.00
50 UNITS
CHF 1’670.00
CHF 842.00
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20 UNITS
CHF 842.00
50 UNITS
CHF 1’670.00
About This Item
CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352204
NACRES:
NA.54
CHF 842.00
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Hersteller von Diagnostika sollten Produkte einer anderen Qualität verwenden: SRE0008
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Empfohlene Produkte
Typ
Type IV
Qualitätsniveau
Form
lyophilized powder
Spezifische Aktivität
20-60 units/mg protein (modified Warburg-Christian)
Zusammensetzung
Protein, 15-35%
Fremdaktivität
6-phosphogluconate dehydrogenase ≤0.5%
UDP glucose pyrophosphorylase and galactokinase ≤0.2%
Lagertemp.
−20°C
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Allgemeine Beschreibung
Research area: Cell Signaling
Galactose-1-phosphate uridyltransferase (GALT) is a galactose metabolizing enzyme that facilitates the simultaneous conversion of uridine diphosphoglucose (UDP-glucose) and galactose-1-phosphate (gal-1P) to uridine diphosphogalactose (UDP-galactose) and glucose-1-phosphate. Classic Galactosemia (CG) is an inherited metabolic condition caused by deficiency of GALT activity.[1] GALT gene is mapped to human chromosome 9p13.[2] Deficiency of GALT results in type 1 galactosemia.[1]
Galactose-1-phosphate uridyltransferase (GALT) is a galactose metabolizing enzyme that facilitates the simultaneous conversion of uridine diphosphoglucose (UDP-glucose) and galactose-1-phosphate (gal-1P) to uridine diphosphogalactose (UDP-galactose) and glucose-1-phosphate. Classic Galactosemia (CG) is an inherited metabolic condition caused by deficiency of GALT activity.[1] GALT gene is mapped to human chromosome 9p13.[2] Deficiency of GALT results in type 1 galactosemia.[1]
Anwendung
Galactose-1-phosphate Uridyltransferase from galactose-adapted yeast has been used to perform enzyme assays.
Einheitendefinition
One unit will form 1.0 μmole of glucose 1-phosphate from UDP-glucose, galactose 1-phosphate and NADP+ per min at pH 8.7 at 25 °C as detected by a coupled system using phosphoglucomutase.
Physikalische Form
Contains buffer salts as citrate and reduced glutathione
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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All monodeoxygenated galactoses were treated with galactokinase, and for the 2-, 3-, and 4-deoxy compounds, transformation into the corresponding galactopyranosyl phosphates could be observed. In case of the 2-deoxy derivative, further reaction via UDP-2-deoxy-D-lyxo-hexose (UDP-2-deoxygalactose), which was also obtained chemically
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