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D8517

Sigma-Aldrich

Eisen-Dextran

95-105 mg/mL (Iron content), solution

Synonym(e):

Ferric hydroxide dextran complex

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About This Item

CAS-Nummer:
9004-66-4
MDL-Nummer:
MFCD00081553
UNSPSC-Code:
12352201
NACRES:
NA.25

Biologische Quelle

synthetic

Qualitätsniveau

200

Sterilität

aseptically filled

Assay

95-105 mg/mL (Iron content)

Form

solution

Enthält

0.5% phenol as preservative

Zusammensetzung

Iron, ~100 mg/mL

Farbe

brown

Nützlicher pH-Bereich

4 - 6.5

Lagertemp.

room temp

InChI

1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)

InChIKey

MVZXTUSAYBWAAM-UHFFFAOYSA-N

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Anwendung

Iron-Dextran (ferric hydroxide dextran complex) may be used as an intravenous iron delivery preparation. Iron-Dextran may be used to induce iron-overload to study its effects and preventative measures.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Piktogramme

Health hazardExclamation mark
GHS08,GHS07

Signalwort

Danger

H-Sätze

H317,H350

Gefahreneinstufungen

Carc. 1B - Skin Sens. 1

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Yonggang Gao et al.
Journal of ethnopharmacology, 145(1), 254-260 (2012-11-14)
Danshen (Salvia miltiorrhiza) has been widely prescribed in traditional folk medicine for treatment of hepatic and cardiovascular diseases in China and other Asian countries for several hundred years. Sixty male mice were randomly divided into five groups: control, iron overload
Raymond J Bergeron et al.
Journal of medicinal chemistry, 51(13), 3913-3923 (2008-06-07)
A series of iron-clearing efficiencies (ICEs), ferrokinetics, and toxicity studies for ( S)-2-(2,4-dihydroxyphenyl)-4,5-dihydro-4-methyl-4-thiazolecarboxylic acid (deferitrin, 1), ( S)-4,5-dihydro-2-[2-hydroxy-4-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylic acid ( 2), and (S)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylic acid ( 3) are reported. The ICEs in rodents are shown to be dose-dependent and saturable for
Natacha E Piloni et al.
Toxicology, 314(1), 174-182 (2013-10-15)
An in vivo model in rat was developed by intraperitoneally administration of Fe-dextran to study oxidative stress triggered by Fe-overload in rat brain. Total Fe levels, as well as the labile iron pool (LIP) concentration, in brain from rats subjected
Zachariah DeFilipp et al.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 9(1), 129-132 (2012-08-08)
Iron deficiency is a major postoperative complication of Roux-en-Y gastric bypass surgery. Oral replacement can fail to correct the deficiency. Thus, recourse to parenteral iron administration might be necessary. Our objective was to evaluate the effectiveness and safety of a
Markus R Jahn et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 78(3), 480-491 (2011-03-29)
The treatment of iron deficiency anemia with polynuclear iron formulations is an established therapy in patients with chronic kidney disease but also in other disease areas like gastroenterology, cardiology, oncology, pre/post operatively and obstetrics' and gynecology. Parenteral iron formulations represent
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