D1260

Decamethoniumbromid

crystalline

• Synonym(e): Decamethylen-bis(trimethylammoniumbromid), Decan-1,10-bis-trimethylammoniumbromid
• Lineare Formel: (CH₃)₃N(Br)(CH₂)₁₀N(Br)(CH₃)₃
• CAS-Nummer: 541-22-0
• Molekulargewicht: 418.29
• UNSPSC Code: 12352200
• NACRES: NA.77
• PubChem Substance ID: 24277833
• EC Number: 208-772-2
• Beilstein/REAXYS Number: 3728288
• MDL number: MFCD00011779
• Form: crystalline

Eigenschaften

• form: crystalline
• Quality Segment: 200
• color: off-white
• mp: 263-267 °C (lit.)
• originator: GlaxoSmithKline
• SMILES string: [Br-].[Br-].C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C
• InChI: 1S/C16H38N2.2BrH/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2
• InChI key: HLXQFVXURMXRPU-UHFFFAOYSA-L
• Gene Information: human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143), CHRND(1144), CHRNE(1145), CHRNG(1146)

Beschreibung

Application

Decamethonium bromide has been used to induce paralysis in duck embryo.

Biochem/physiol Actions

Nicotinic acetylcholine receptor partial agonist and neuromuscular blocking agent; depolarizes striated muscles and blocks their activity.

Decamethonium serves as a muscle relaxant and is also a neuromuscular blocking agent. It has a molecular weight of 258.4.[1]

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H315,H319,H335
• pcodes: P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges