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C3305

Sigma-Aldrich

Carbacyclin

≥90% (HPLC)

Synonym(e):

6a-Carba-prostaglandin I2, Carbocyclic PGI2

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About This Item

Empirische Formel (Hill-System):
C21H34O4
CAS-Nummer:
69552-46-1
Molekulargewicht:
350.49
MDL-Nummer:
MFCD00210824
UNSPSC-Code:
12352211
PubChem Substanz-ID:
24892602

Assay

≥90% (HPLC)

Lagertemp.

−20°C

SMILES String

[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)CCCCC)[C@@]1([H])CC(\C2)=C\CCCC(O)=O

InChI

1S/C21H34O4/c1-2-3-4-8-17(22)10-11-18-19-13-15(7-5-6-9-21(24)25)12-16(19)14-20(18)23/h7,10-11,16-20,22-23H,2-6,8-9,12-14H2,1H3,(H,24,25)/b11-10+,15-7+/t16-,17-,18+,19-,20+/m0/s1

InChIKey

XZFRIPGNUQRGPI-WBQKLGIQSA-N

Angaben zum Gen

human ... PPARA(5465) , PPARD(5467) , PPARG(5468)

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
108K1386
120M1748
056K1562
036K1444
108H1220

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R A Gupta et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(24), 13275-13280 (2000-11-23)
There is evidence from both genetic and pharmacologic studies to suggest that the cyclooxygenase-2 (COX-2) enzyme plays a causal role in the development of colorectal cancer. However, little is known about the identity or role of the eicosanoid receptor pathways
Chuan-Ming Hao et al.
The Journal of biological chemistry, 277(24), 21341-21345 (2002-04-03)
COX2-selective non-steroidal anti-inflammatory drugs (NSAIDs) cause selective apoptosis of renal medullary interstitial cells (RMIC) in vivo and reduce their ability to tolerate hypertonic stress in vitro. To determine the mechanism by which COX2 activity promotes RMIC viability, we examined the
M J Kim et al.
Molecular genetics and metabolism, 74(3), 362-369 (2001-11-16)
We have found that sebaceous epithelial cell (sebocyte) differentiation is induced by cognate ligand-agonists of either peroxisome proliferator-activated receptors (PPARs) or retinoid X receptors (RXRs). In this study, we tested the hypothesis that PPAR-RXR cooperation is used in sebocytes as
A C Maurin et al.
Calcified tissue international, 76(5), 385-392 (2005-05-04)
As previously reported, the age-related association between bone loss and increased marrow adipose volume may involve inhibitory effects of polyunsaturated fatty acids (PUFAs) potentially released by medullary adipocytes on osteoblastic proliferation and cell cycle progression. Because PUFAs have been reported
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