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Merck

B4651

Sigma-Aldrich

3-Brom-3-methyl-2-(2-nitrophenylthio)-3H-indol

≥85%

Synonym(e):

2-(2-Nitrophenyl-sulfenyl)-3-methyl-3-brom-indolenin, 3-Brom-3-methyl-2-(2-nitrophenylmercapto)-3H-indol, BNPS-Skatol

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About This Item

Empirische Formel (Hill-System):
C15H11BrN2O2S
CAS-Nummer:
Molekulargewicht:
363.23
Beilstein:
1491457
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:

Assay

≥85%

Lagertemp.

−20°C

SMILES String

CC1(Br)C(Sc2ccccc2[N+]([O-])=O)=Nc3ccccc13

InChI

1S/C15H11BrN2O2S/c1-15(16)10-6-2-3-7-11(10)17-14(15)21-13-9-5-4-8-12(13)18(19)20/h2-9H,1H3

InChIKey

BXTVQNYQYUTQAZ-UHFFFAOYSA-N

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Anwendung

Peptid-Spaltungsreagens spezifisch für Carboxylgruppen des Tryptophanrests.

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Hee-Kyoung Lee et al.
Biochemical and biophysical research communications, 315(1), 1-9 (2004-03-12)
Squalene epoxidase (SE) catalyzes the conversion of squalene to (3S)-2,3-oxidosqualene. Photolabeling and site-directed mutagenesis were performed on recombinant rat SE (rrSE) in order to identify the location of the substrate-binding site and the roles of key residues in catalysis. Truncated
V Rahali et al.
Journal of protein chemistry, 18(1), 1-12 (1999-03-11)
A comparative study of various procedures for tryptophanyl peptide bond cleavage by BNPS-skatole [2-(2-nitrophenyl)-3-methyl-3-bromoindolenine] was carried out on native and on reduced and alkylated bovine beta-lactoglobulin (BLG). The reaction yield and the composition of the derived products were studied in
J E Moskaitis et al.
Neurochemical research, 11(2), 299-315 (1986-02-01)
The interactions of sodium dodecyl sulfate with a number of proteins were examined at a variety of pH values ranging from 4.8 to 11.6. The dodecyl sulfate-induced precipitation of some of these proteins was observed within a relatively limited range
The core domain of hirudin from the leech Hirudinaria manillensis. Chemical modification of a tryptophan-containing synthetic peptide analog.
F De Antoni et al.
Advances in experimental medicine and biology, 398, 627-633 (1996-01-01)
J Schaller et al.
Protein sequences & data analysis, 4(2), 69-74 (1991-08-01)
The complete amino acid sequence of equine miniplasminogen (Mr 37,132, 338 residues) was determined with the aid of fragments obtained by cleavage with 2-(2-nitrophenylsulfenyl)-3-methyl-3'-bromoindolenine, cyanogen bromide or clostripain. The fragments were aligned with overlapping sequences. Sequence comparison with other species

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