A5730

Abz-SDK(Dnp)P-OH -trifluoracetat (Salz)

≥91% (HPLC), lyophilized powder

• Synonym(e): o-aminobenzoic acid-Ser-Asp-Lys(DNP)Pro-OH -trifluoracetat (Salz)
• Empirische Formel (Hill-System): C₃₁H₃₈N₈O₁₃ · xC₂HF₃O₂
• CAS-Nummer: 1217465-57-0
• Molekulargewicht: 730.68 (free base basis)
• NACRES: NA.77
• PubChem Substance ID: 24891013
• UNSPSC Code: 12352200
• MDL number: MFCD09753055
• Assay: ≥91% (HPLC)
• Form: lyophilized powder

Eigenschaften

• Quality Segment: 100
• assay: ≥91% (HPLC)
• form: lyophilized powder
• solubility: H₂O: freely soluble
• storage temp.: 2-8°C
• SMILES string: OC(=O)C(F)(F)F.Nc1ccccc1C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCNc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)C(=O)N3CCC[C@H]3C(O)=O
• InChI: 1S/C31H38N8O13.C2HF3O2/c32-19-7-2-1-6-18(19)27(43)36-23(16-40)29(45)35-22(15-26(41)42)28(44)34-21(30(46)37-13-5-9-24(37)31(47)48)8-3-4-12-33-20-11-10-17(38(49)50)14-25(20)39(51)52;3-2(4,5)1(6)7/h1-2,6-7,10-11,14,21-24,33,40H,3-5,8-9,12-13,15-16,32H2,(H,34,44)(H,35,45)(H,36,43)(H,41,42)(H,47,48);(H,6,7)/t21-,22-,23-,24-;/m0./s1
• InChI key: IFSUGURCQHMSJS-JPIABUGISA-N

Beschreibung

Application

Abz-SDK(Dnp)P-OH trifluoroacetate is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate that specifically binds to the N domain of ACE. Abz-SDK(Dnp)P-OH has been used to study tipifarnib-induced apoptosis in acute myeloid leukemia and multiple myeloma cells.

Biochem/physiol Actions

Abz-SDK(Dnp)P-OH is an Angiotensin Converting Enzyme (ACE) fluorescent peptide substrate specific for the N domain for real time fluorescent assay (ACE, Peptidyl Dipeptidase, Kininase II, E.C. 3.4.15.1).

Features and Benefits

This compound is featured on the Angiotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable