A211030

DMT-2′O-TBDMS-rA(bz)-phosphoramidit

configured for ABI

• Synonym(e): DMT-2’O-TBDMS-rA(bz)-amidit, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-adenosin, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidit]
• Empirische Formel (Hill-System): C₅₃H₆₆N₇O₈PSi
• CAS-Nummer: 104992-55-4
• Molekulargewicht: 988.19
• MDL-Nummer: MFCD00080297
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329770733
• NACRES: NA.51

Eigenschaften

• Biologische Quelle: non-animal source (no BSE/TSE risk)
• Produktlinie: Proligo Reagents
• Assay: ≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
• Form: powder
• Methode(n): oligo synthesis: suitable
• Verunreinigungen: ≤0.3% water content (Karl Fischer); ≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR); ≤0.5% single Impurity (reversed phase HPLC); ≤3% residual Solvent content
• Farbe: white to off-white
• λ: conforms (UV/VIS Identity)
• Eignung: conforms to structure for H-NMR; conforms to structure for LC-MS
• Kompatibilität: configured for ABI
• Nukleosidprofil: base: adenosine; base protecting group: benzoyl; 2' protecting group: TBDMS; 5' protecting group: DMT; deprotection: standard
• Lagertemp.: −20°C
• SMILES String: COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)c5ccccc5)ncnc34)(c6ccccc6)c7ccc(OC)cc7
• InChI: 1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1
• InChIKey: FFXHNCNNHASXCT-RFMFGJHUSA-N

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable