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A1263

Sigma-Aldrich

DL-Amphetamin -sulfat (Salz)

Synonym(e):

(±)-α-Methylphenethylamine sulfate salt

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About This Item

Lineare Formel:
C18H26N2 · H2SO4
CAS-Nummer:
60-13-9
Molekulargewicht:
368.49
EG-Nummer:
200-457-8
MDL-Nummer:
MFCD00070254
UNSPSC-Code:
12352116
PubChem Substanz-ID:
329770696
NACRES:
NA.77

Form

powder

Qualitätsniveau

100

Arzneimittelkontrolle

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

Anwendung(en)

forensics and toxicology

SMILES String

OS(O)(=O)=O.CC(N)Cc1ccccc1.CC(N)Cc2ccccc2

InChI

1S/2C9H13N.H2O4S/c2*1-8(10)7-9-5-3-2-4-6-9;1-5(2,3)4/h2*2-6,8H,7,10H2,1H3;(H2,1,2,3,4)

InChIKey

PYHRZPFZZDCOPH-UHFFFAOYSA-N

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Anwendung

DL-Amphetamine sulfate salt has been used to induce place preference in rats to study the effect of diazepam and zolpidem. It has also been used as a drug standard in the digital image-based colorimetric presumptive test.

Biochem./physiol. Wirkung

DL -Amphetamine, also known as benzedrine, is a synthetic stimulant. It is usually produced as a sulfate salt (DL-amphetamine sulfate salt). DL-Amphetamine sulfate may be used to treat children with behavior disorders., Induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites; blocks catecholamine reuptake.

Piktogramme

Skull and crossbonesHealth hazard
GHS06,GHS08

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 3 - Repr. 2 - STOT RE 2 - STOT SE 3

Zielorgane

Brain, Respiratory system

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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Madeleine P Strohl
The Yale journal of biology and medicine, 84(1), 27-33 (2011-04-01)
In 1937, psychiatrist Charles Bradley administered Benzedrine sulfate, an amphetamine, to "problem" children at the Emma Pendleton Bradley Home in Providence, Rhode Island, in an attempt to alleviate headaches; however, Bradley noticed an unexpected effect upon the behavior of the
Aree Choodum et al.
Drug testing and analysis, 3(5), 277-282 (2011-03-10)
Digital image analysis was applied to the products of simple colorimetric [corrected] tests for amphetamine and methylamphetamine. Adobe Photoshop software was used for colour analysis to obtain analytical data in the form of a Red Green Blue (RGB) value. Calibration
E Meririnne et al.
Pharmacology, biochemistry, and behavior, 62(1), 159-164 (1999-02-11)
Drugs such as benzodiazepines, which enhance the effects of inhibitory neurotransmitter gamma-amino butyric acid (GABA), are known to modulate the mesocorticolimbic dopaminergic system, which is considered to mediate the rewarding effects of psychostimulants. The effects of diazepam, a benzodiazepine that
Rita Perfeito et al.
Free radical biology & medicine, 62, 186-201 (2013-06-08)
Parkinson disease (PD) is a chronic and progressive neurological disease associated with a loss of dopaminergic neurons. In most cases the disease is sporadic but genetically inherited cases also exist. One of the major pathological features of PD is the
Mark A Sembower et al.
Journal of addictive diseases, 32(1), 26-38 (2013-03-14)
This article examines rates of nonmedical use and diversion of extended-release amphetamine and extended-release oral methylphenidate in the United States. Prescription dispensing data were sourced from retail pharmacies. Nonmedical use data were collected from the Researched Abuse, Diversion and Addiction-Related
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