If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf
Wichtige Dokumente
81709
L-Prolin
≥99.5% (NT), suitable for cell culture, BioUltra
Synonym(e):
(S)-Pyrrolidin-2-carbonsäure
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About This Item
Empfohlene Produkte
Produktbezeichnung
L-Prolin, BioUltra, ≥99.5% (NT)
Produktlinie
BioUltra
Assay
≥99.5% (NT)
Form
powder or crystals
Optische Aktivität
[α]20/D −85.0±1.0°, c = 5% in H2O
Methode(n)
cell culture | mammalian: suitable
Verunreinigungen
insoluble matter, passes filter test
≤0.3% foreign amino acids
Glührückstand
≤0.1%
Verlust
≤0.1% loss on drying, 20 °C (HV)
Farbe
colorless to white
pH-Wert
6.0-7.0 (25 °C, 1 M in H2O)
mp (Schmelzpunkt)
228 °C (dec.) (lit.)
Löslichkeit
H2O: 1 M at 20 °C, clear, colorless
Anionenspuren
chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤100 mg/kg
Kationenspuren
Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤20 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg
λ
1 M in H2O
UV-Absorption
λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05
SMILES String
OC(=O)[C@@H]1CCCN1
InChI
1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
InChIKey
ONIBWKKTOPOVIA-BYPYZUCNSA-N
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Anwendung
- Synthesis and in silico inhibitory action studies of azo-anchored imidazo[4,5-b]indole scaffolds against the COVID-19 main protease (M(pro)).: This publication discusses the synthesis of novel compounds using L-Proline and their potential as inhibitors against COVID-19, contributing to the ongoing search for effective treatments (Geedkar et al., 2024).
Lagerklassenschlüssel
13 - Non Combustible Solids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Artikel
Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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