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62225

Sigma-Aldrich

2-Linoleoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamin

≥98.0% (10 mg phospholipid per ml CHCl3, TLC)

Synonym(e):

3-sn-Phosphatidylethanolamin, 2-linoleoyl-1-palmitoyl, L-β-Linoleoyl-γ-palmitoyl-α-cephalin

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About This Item

Empirische Formel (Hill-System):
C39H74NO8P
CAS-Nummer:
13206-00-3
Molekulargewicht:
715.98
Beilstein:
2033925
MDL-Nummer:
MFCD00058604
UNSPSC-Code:
12352211
PubChem Substanz-ID:
329759720

Biologische Quelle

synthetic

Assay

≥98.0% (10 mg phospholipid per ml CHCl3, TLC)

Form

liquid

Funktionelle Gruppe

phospholipid

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

CCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(=O)OCCN)OC(=O)CCCCCCC\C=C\C\C=C\CCCCC

InChI

1S/C39H74NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h11,13,17-18,37H,3-10,12,14-16,19-36,40H2,1-2H3,(H,43,44)/b13-11+,18-17+/t37-/m0/s1

InChIKey

HBZNVZIRJWODIB-KPMVPPRFSA-N

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Anwendung

2-Linoleoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamine is the substrate for human group V phospholipase A2 . In addition, 2-Linoleoyl-1-palmitoyl-sn-glycero-3-phosphoethanolamine provides an in vitro model for studying and a diagnosis tool for diagnosis of oxidative stress .

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Piktogramme

Skull and crossbonesHealth hazard
GHS06,GHS08

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Zielorgane

Central nervous system

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

M Rosário M Domingues et al.
Biomedical chromatography : BMC, 23(6), 588-601 (2009-03-12)
Phosphatidylethanolamines are a major class of phospholipids found in cellular membranes. Identification of the alterations in these phospholipids, induced by free radicals, could provide new tools for in vivo diagnosis of oxidative stress. In this study, 1-palmitoyl-2-linoleoyl-phosphatidylethanolamine oxidation products, induced
Lucas G Sosa Alderete et al.
Plant physiology and biochemistry : PPB, 151, 411-420 (2020-04-14)
Glycerophospholipids (GPLs) from cell membranes (CM) are a proper source for the synthesis of lipid messengers able to activate signal pathways that will define the plant survival under changing and stressful environmental conditions. Little is known about how GPLs metabolism
Y Chen et al.
Biochimica et biophysica acta, 1394(1), 57-64 (1998-10-10)
Group V phospholipase A2 (GV-PLA2) has been shown to be involved in signal transduction and inflammatory processes in cellular studies, but the physical and biochemical properties of this important enzyme have been unclear. We report the over-expression and characterization of
Md Abdullah Al Sazzad et al.
Biophysical journal, 117(1), 36-45 (2019-05-28)
Ceramide-1-phosphate is a minor sphingolipid with important functions in cell signaling. In this study, we examined the propensity of palmitoyl ceramide-1-phosphate (Cer-1P) to segregate laterally into ordered domains in different bilayer compositions at 23 and 37°C and compared this with
Zhixu Ni et al.
Scientific reports, 7(1), 15138-15138 (2017-11-11)
Oxidized phospholipids (oxPLs) have been recently recognized as important mediators of various and often controversial cellular functions and stress responses. Due to the low concentrations in vivo, oxPL detection is mostly performed by targeted mass spectrometry. Although significantly improving the sensitivity
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