460R-1

Heat Shock Protein 70 (EP377) Rabbit Monoclonal Primary Antibody

• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100; 500
• Konjugat: unconjugated
• Antikörperform: culture supernatant
• Antikörper-Produkttyp: primary antibodies
• Klon: EP377, monoclonal
• Beschreibung: For In Vitro Diagnostic Use in Select Regions
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Verpackung: vial of 0.1 mL concentrate (460R-14); vial of 0.1 mL concentrate Research Use Only (460R-14-RUO); vial of 0.5 mL concentrate (460R-15); vial of 1.0 mL concentrate (460R-16); vial of 1.0 mL concentrate Research Use Only (460R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (460R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (460R-17); vial of 7.0 mL pre-dilute ready-to-use (460R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (460R-18-RUO)
• Hersteller/Markenname: Cell Marque^®
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotyp: IgG
• Kontrolle: hepatocellular carcinoma
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Visualisierung: cytoplasmic, nuclear
• Angaben zum Gen: human ... HSPA1A(3303)

Beschreibung

Allgemeine Beschreibung

The Heat Shock Protein 70 family of highly conserved chaperone proteins increase in expression upon exposure to stress factors such as temperature shock, hypoxia, oxidative stress, and pH change.[1] This promotes cell survival by repairing misfolded proteins and preventing protein aggregates, among other functions.[1] Likewise, tumor cells can use this mechanism to confer a survival advantage as demonstrated in Heat Shock Protein 70 overexpression in hepatocellular carcinoma.[2][3][4][5][1]

Qualität

United States - IVD
European Union - IVD
Japan - RUO

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Angaben zur Herstellung

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Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: [email protected]

Rechtliche Hinweise

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2