431R-1

Islet-1 (EP283) Rabbit Monoclonal Primary Antibody

• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100; 500
• Konjugat: unconjugated
• Antikörperform: culture supernatant
• Antikörper-Produkttyp: primary antibodies
• Klon: EP283, monoclonal
• Beschreibung: (For In Vitro Diagnostic Use in Select Regions (See Chart))
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Verpackung: bottle of 1.0 mL predilute (431R-17); bottle of 7.0 mL predilute (431R-18); vial of 0.1 mL concentrate (431R-14); vial of 0.5 mL concentrate (431R-15); vial of 1.0 mL concentrate (431R-16)
• Hersteller/Markenname: Cell Marque^™
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
• Isotyp: IgG
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Angaben zum Gen: human ... ISL1(3670)

Beschreibung

Allgemeine Beschreibung

Islet-1, a human insulin gene enhancer-binding protein, is a transcription factor involved in the differentiation of the neuroendocrine pancreatic cells.^1-3 Islet-1 plays an important role in the embryogenesis and differentiation of the insulin producing pancreatic beta cells within the islets of Langerhans.³ Neuroendocrine tumors can arise from a variety of primary sites, most commonly in the bronchopulmonary system, gastrointestinal (GI) tract, and pancreas.² Neuroendocrine tumors of the GI tract and pancreas tend to be slow growing and indolent, and may metastasize to the liver before it is detected.² Islet-1 exhibits strong nuclear staining in the islets of normal pancreas and tumor cells of the pancreatic neuroendocrine tumor.^1-3 Islet-1 has been shown to be a reliable marker for the detection of primary and metastatic pancreatic neuroendocrine neoplasms.^1-3

Qualität

IVD

IVD

IVD

RUO

Verlinkung

Islet-1 Positive Control Slides, Product No. 431S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Angaben zur Herstellung

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable