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30382

Sigma-Aldrich

Cytochalasin C aus Metarrhizium anisopliae

≥97.0% (TLC)

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About This Item

Empirische Formel (Hill-System):
C30H37NO6
CAS-Nummer:
22144-76-9
Molekulargewicht:
507.62
Beilstein:
1613194
EG-Nummer:
244-803-6
MDL-Nummer:
MFCD00066080
UNSPSC-Code:
12352202
PubChem Substanz-ID:
329753489
NACRES:
NA.77

Biologische Quelle

Metarrhizium anisopliae

Assay

≥97.0% (TLC)

Form

fibers
powder

Löslichkeit

methylene chloride: 5 mg/mL, clear, colorless

Lagertemp.

−20°C

SMILES String

C[C@@H]1C\C=C\[C@H]2[C@H](O)C(C)=C(C)C3[C@H](Cc4ccccc4)NC(=O)[C@@]23C(OC(C)=O)\C=C\[C@@](C)(O)C1=O

InChI

1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17,22-26,33,36H,10,16H2,1-5H3,(H,31,35)/b13-9+,15-14+/t17-,22+,23+,24-,25?,26-,29-,30-/m1/s1

InChIKey

NAIODHJWOHMDJX-QMTXKCDBSA-N

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Sonstige Hinweise

Structure of cytochalasins and cytochalasin B binding sites in human erythrocyte membranes

Piktogramme

Skull and crossbonesHealth hazard
GHS06,GHS08

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2

Lagerklassenschlüssel

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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H Haimoto et al.
The American journal of pathology, 121(2), 185-191 (1985-11-01)
To elucidate the changes of ultrastructural localization of S-100 protein during lipolysis in adipocytes, an immunoelectron-microscopic study was performed. Epididymal fat pads from Wistar rats were incubated in the buffer with or without 10 microM epinephrine. Before incubation with epinephrine
M Varedi et al.
Journal of cellular physiology, 172(2), 192-199 (1997-08-01)
Cytoskeleton not only controls cell morphology but also regulates cell growth, migration, differentiation, and gene expression, events which are fundamental to embryogenesis, carcinogenesis, and wound healing. We have recently reported that reorganization of cytoskeleton induces expression of mRNA for transforming
J Thyberg et al.
Virchows Archiv. B, Cell pathology including molecular pathology, 59(1), 1-10 (1990-01-01)
The transition of adult rat aortic smooth muscle cells from a contractile to a synthetic phenotype during the first week of primary culture on a substrate of fibronectin in serum-free medium was studied by light and electron microscopy. The weak
V G Lukashin et al.
Morfologiia (Saint Petersburg, Russia), 118(4), 41-45 (2003-03-13)
Colchicine and cytochalasine C exert modifying action on tissue receptors of urinary bladder of the frog. Under the effect of cytochalasine the period of vital staining of receptors were changed. Latent period of decoloration grew 37-56% longer while the period
Jeffrey C Nolz et al.
Journal of immunology (Baltimore, Md. : 1950), 179(2), 1104-1112 (2007-07-10)
TCR/CD28 engagement triggers the initiation of a variety of signal transduction pathways that lead to changes in gene transcription. Although reorganization of the actin cytoskeleton is required for T cell activation, the molecular pathways controlled by the actin cytoskeleton are
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