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Merck

PHR2006

Supelco

Allopurinol-verwandte Verbindung B

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

3-(Formylamino)-1H-pyrazol-4-carboxamid, 5-(Formylamino)-1H-pyrazol-4-carboxamid

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About This Item

Empirische Formel (Hill-System):
C5H6N4O2
CAS-Nummer:
Molekulargewicht:
154.13
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to BP 832
traceable to Ph. Eur. A0350020
traceable to USP 1013013

API-Familie

allopurinol

Analysenzertifikat (CofA)

current certificate can be downloaded

Verpackung

pkg of 50 mg

Anwendung(en)

pharmaceutical

Format

neat

Lagertemp.

2-8°C

InChI

1S/C5H6N4O2/c6-4(11)3-1-8-9-5(3)7-2-10/h1-2H,(H2,6,11)(H2,7,8,9,10)

InChIKey

MKVXRGIJTKYXPR-UHFFFAOYSA-N

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Allgemeine Beschreibung

Allopurinol Related Compound B is an impurity of allopurinol. Allopurinol is a purine analog and a structural isomer of the naturally available purine in the body, hypoxanthine. It is also a powerful xanthine oxidase inhibitor. It is widely utilized against purine and pyrimidine metabolic disorders that give rise to an excess of uric acid in humans.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Allopurinol Related Compound B may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAB7872 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Development of a stability indicating RP-RRLC method for determination of allopurinol and its degradation products in solid oral dosage
Singh S and Gadhawala Z
International Journal of PharmTech Research, 5(1), 44-53 (2013)
Allopurinol
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 34(1), 132-132 (2018)
High-performance liquid chromatography with polarographic and voltammetric anodic detection: simultaneous determination of allopurinol, oxipurinol and uric acid in body fluids
Palmisano F, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 306(1), 205-214 (1984)

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