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M1851000

Metronidazolbenzoat

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

(2-Methyl-5-nitro-1H-imidazol-1-ethyl)-benzoat

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About This Item

Empirische Formel (Hill-System):
C13H13N3O4
CAS-Nummer:
Molekulargewicht:
275.26
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

metronidazole

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

InChI

1S/C13H13N3O4/c1-10-14-9-12(16(18)19)15(10)7-8-20-13(17)11-5-3-2-4-6-11/h2-6,9H,7-8H2,1H3

InChIKey

CUUCCLJJOWSASK-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Metronidazole benzoate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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S M Ross et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 63(15), 566-567 (1983-04-09)
Antenatal patients free of Trichomonas vaginalis vaginal infection were compared with infected patients, half of whom were treated and half left untreated. The treated group was given benzoylmetronidazole 50 ml (2 g metronidazole equivalent) as a single dose. The mode
[HPLC determination of benzoylmetronidazole and metronidazole in biological materials].
J Avramova
Die Pharmazie, 43(6), 436-436 (1988-06-01)
G Takács
Therapia Hungarica (English edition), 40(4), 189-191 (1992-01-01)
Klion suspension was given to 42 girl and woman patients suffering from vaginal trichomoniasis. Negativity for Trichomonas was recorded in 73.8% of the cases in response to the first 10-day cure, and in 90.5% of the patients following repeated cures.
B Bloch et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 67(12), 455-457 (1985-03-23)
Metronidazole tablets, benzoyl metronidazole suspension and tinidazole tablets each given as a single 2 g bolus dose in an open controlled prospective study were found to be effective forms of treatment for Trichomonas vaginalis vaginitis. The cure rates on wet
J A Ogunbanwo et al.
FEMS immunology and medical microbiology, 30(1), 73-83 (2001-02-15)
The trypanosomostatic and trypanosomicidal effects of four anti-protozoal drugs, namely halofantrine hydrochloride, chloroquine phosphate, benzoylmetronidazole and pyrimethamine, on species of trypanosomes, viz. Trypanosoma brucei brucei (MBOS/NG/94/NITR) Bassa strain, T. congolense (MBOS/NG/93/NVRI) Zaria strain and T. brucei gambiense (MHOM/NG/92/NITR) Abraka strain

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