89397

Girard-Reagenz T

for HPLC derivatization, LiChropur^™, 99.0-101.0% (AT)

• Synonym(e): (Carboxymethyl)-trimethylammonium-chlorid-hydrazid, (Hydrazinocarbonylmethyl)-trimethylammoniumchlorid, Acethydrazid-trimethylammoniumchlorid
• Lineare Formel: [(CH₃)₃N⁺CH₂CONHNH₂]Cl^-
• CAS-Nummer: 123-46-6
• Molekulargewicht: 167.64
• Beilstein: 3727163
• EG-Nummer: 204-629-3
• MDL-Nummer: MFCD00012009
• UNSPSC-Code: 12000000
• PubChem Substanz-ID: 329769730
• NACRES: NA.22

Eigenschaften

• Qualität: for HPLC derivatization; LiChropur^™
• Qualitätsniveau: 100
• Assay: 99.0-101.0% (AT)
• Form: crystals
• Methode(n): HPLC: suitable
• mp (Schmelzpunkt): 188-192 °C (dec.) (lit.)
• SMILES String: [Cl-].C[N+](C)(C)CC(=O)NN
• InChI: 1S/C5H13N3O.ClH/c1-8(2,3)4-5(9)7-6;/h4,6H2,1-3H3;1H
• InChIKey: YSULOORXQBDPCU-UHFFFAOYSA-N

Beschreibung

Anwendung

Girard′s reagent T may be used as a derivatizing reagent for the determination of 5-Formyl-2′-deoxyuridine in cellular DNA samples using liquid chromatography–tandem mass spectrometry (LC–MS/MS) technique. Reducing saccharides can be derivatized by Girard′s reagent T and this can be analyzed by matrix-assisted laser desorption/ionization coupled to time of flight mass spectrometry (MALDI-TOF-MS) technique.

Leistungsmerkmale und Vorteile

• Girard′s reagent T is a chemical derivatization reagent for LC-MS.
• It has carbonyl functional group possessing high proton (cation) affinity that stabilizes a positive charge.       
• It is commonly used in the derivatization of nucleosides.        
• Derivatization reactions in mass spectrometry are used to improve ionization efficiency.
• Derivatization can enhance precise quantitative analysis for profiling of relatively small analyte molecules, particularly in metabolomics.

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Rechtliche Hinweise

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable