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Merck

76735

Supelco

O-(2,3,4,5,6-Pentafluorbenzyl)-hydroxylamin -hydrochlorid

for GC derivatization, LiChropur, ≥99.0% (AT)

Synonym(e):

PFBHA.HCl

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1 G
CHF 258.00
10 X 1 G
CHF 1’050.00

CHF 258.00


Voraussichtliches Versanddatum29. Mai 2025


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1 G
CHF 258.00
10 X 1 G
CHF 1’050.00

About This Item

Lineare Formel:
C6F5CH2ONH2·HCl
CAS-Nummer:
Molekulargewicht:
249.57
Beilstein:
4031190
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12000000
PubChem Substanz-ID:
NACRES:
NA.22

CHF 258.00


Voraussichtliches Versanddatum29. Mai 2025


Bulk-Bestellung anfordern

Qualität

derivatization grade ((GC derivatization))
for GC derivatization
LiChropur

Qualitätsniveau

Assay

≥99.0% (AT)

Form

solid

Eignung der Reaktion

reagent type: derivatization reagent
reaction type: Alkylations

Methode(n)

gas chromatography (GC): suitable

mp (Schmelzpunkt)

212-218 °C
227 °C (subl.) (lit.)

Löslichkeit

H2O: 5%, clear

SMILES String

Cl.NOCc1c(F)c(F)c(F)c(F)c1F

InChI

1S/C7H4F5NO.ClH/c8-3-2(1-14-13)4(9)6(11)7(12)5(3)10;/h1,13H2;1H

InChIKey

HVMVKNXIMUCYJA-UHFFFAOYSA-N

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Allgemeine Beschreibung

O-(2,3,4,5,6-Pentafluorbenzyl)hydroxylaminhydrochlorid (PFBHA.HCl) ist ein Derivatisierungsmittel.[1]

Anwendung

PFBHA.HCl wird für die Derivatisierung von Metaboliten mit Carbonylgruppen und die anschließende Analyse mittels GC-MS verwendet.[1] Es wird zudem bei der Aldehydderivatisierung und der anschließenden aldehydischen Hydrolyse mittels GC/MS eingesetzt.[2]

Verpackung

Bodenlose Glasflasche Der Inhalt befindet sich innerhalb des eingeschobenen Schmelzkegels.

Sonstige Hinweise

Empfindliches Derivatisierungsreagens für Gaschromatographische Analysen mit Elektroneneinfangdetektor von Verbindungen mit Carbonylgruppen: Keto Steroide und Kohlenhydrate [3]

Rechtliche Hinweise

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Plasmalogen degradation by oxidative stress: production and disappearance of specific fatty aldehydes and fatty alpha-hydroxyaldehydes.
Stadelmann-Ingrand S
Free Radical Biology & Medicine, 31(10), 1263-1271 (2001)
Degradation of fluoranthene by Pasteurella sp. IFA and Mycobacterium sp. PYR-1:isolation and identification of metabolites.
Sepic E, Bricelj M, Leskovsek H.
Journal of Applied Microbiology, 85(4), 746-754 null
S Strassnig et al.
Journal of chromatography. A, 891(2), 267-273 (2000-10-24)
A method for the determination of carbonyl compounds, either directly from gaseous phase or following a volatilization from liquid or solid samples after trapping on Tenax TA is presented. Following solvent desorption, the carbonyls are derivatized using O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine. The reaction
Catherine Tessini et al.
Journal of chromatography. A, 1219, 154-160 (2011-12-14)
HPLC-UV and GC/MS determination of aldehydes in bio-oil were evaluated. HPLC-UV preceded by derivatization with 2,4-dinitrophenylhydrazine allows separation and detection of bio-oil aldehydes, but the derivatization affected the bio-oil stability reducing their quantitative applicability. GC/MS determination of aldehydes was reached
Christiane Collins et al.
Chemical research in toxicology, 16(12), 1560-1566 (2003-12-19)
Deoxyribose oxidation in DNA represents a biologically important facet of oxidative DNA damage that gives rise to protein-DNA cross-links and base adducts. Toward the goal of quantifying deoxyribose oxidation chemistry in cells, we report a method for the quantification of

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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