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Merck

46609

Supelco

Penicillin G Kaliumsalz

VETRANAL®, analytical standard

Synonym(e):

Benzylpenicillin Kaliumsalz

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About This Item

Empirische Formel (Hill-System):
C16H17KN2O4S
CAS-Nummer:
Molekulargewicht:
372.48
Beilstein:
3832841
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
E-Nummer:
E705
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Agentur

EPA 1694

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Wirkungsspektrum von Antibiotika

Gram-positive bacteria

Anwendung(en)

cleaning products
clinical
cosmetics
environmental
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

Format

neat

Wirkungsweise

cell wall synthesis | interferes

Lagertemp.

2-8°C

SMILES String

[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChIKey

IYNDLOXRXUOGIU-LQDWTQKMSA-M

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Allgemeine Beschreibung

Chemical structure: ß-lactam

Anwendung

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Wirkungsweise: Penicillin G wirkt durch Hemmung der Zellwandsynthese durch die Bindung an Penicillin bindende Proteine (PBP), um die Vernetzung der Peptidoglycan-Kette zu hemmen.

Antimikrobielles Spektrum: Diese Produkt ist wirksam gegen grampositive und gramnegative Bakterien.

Vorsicht

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Vasim Ahmed et al.
Journal of biotechnology, 163(4), 419-424 (2013-01-12)
In the present study, a novel strategy was adopted to synthesize, β lactamase resistant penicillin G molecules by using the unique properties of silver nanoparticles. Ascorbic acid-stabilized spherical monodispersed silver nanoparticles were prepared by a simple chemical reaction. The formation
Muneki Hotomi et al.
PloS one, 8(3), e58124-e58124 (2013-03-14)
The protection against pneumococcal infections provided by currently available pneumococcal polysaccharide conjugate vaccines are restricted to the limited number of the serotypes included in the vaccine. In the present study, we evaluated the distribution of the pneumococcal capsular type and
Tina Lund Leunbach et al.
Ugeskrift for laeger, 175(11), 742-743 (2013-03-14)
A pregnant Caucasian woman with newly diagnosed syphilis in the secondary stage was hospitalized for observation while being treated with penicillin. After one dose of penicillin the foetus was delivered by a caesarean section at gestational age 28 weeks +
Nicolas Dupin et al.
Presse medicale (Paris, France : 1983), 42(4 Pt 1), 446-453 (2013-02-19)
Syphilis is back since 2000. Early syphilis comprises primary syphilis, secondary syphilis and early latent syphilis (less than 1 year duration). During early phases of syphilis, patients are more contagious and neurologic complications are rare. Early neurosyphilis are mostly represented
Leticia L Torres et al.
Applied and environmental microbiology, 79(5), 1555-1562 (2012-12-25)
A homologue of the Escherichia coli penicillin acylase is encoded in the genomes of several thermophiles, including in different Thermus thermophilus strains. Although the natural substrate of this enzyme is not known, this acylase shows a marked preference for penicillin

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