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Merck

319112

Sigma-Aldrich

Methylenblau -Lösung

0.05 wt. % in H2O

Synonym(e):

Ehrlichs Reagens III, Loeffler’s Methylenblau

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About This Item

Empirische Formel (Hill-System):
C16H18ClN3S
CAS-Nummer:
Molekulargewicht:
319.85
Farbindexnummer:
52015
Beilstein:
3641570
MDL-Nummer:
UNSPSC-Code:
12171500
PubChem Substanz-ID:
NACRES:
NA.47

Form

liquid

Qualitätsniveau

Konzentration

0.05 wt. % in H2O

Dichte

0.98 g/mL at 25 °C

λmax

665 nm

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

[Cl-].CN(C)c1ccc2N=C3C=C\C(C=C3Sc2c1)=[N+](/C)C

InChI

1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1

InChIKey

CXKWCBBOMKCUKX-UHFFFAOYSA-M

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Anwendung

Methylene Blue solution has been used to study structural alterations and p53 immune-expression in rats.

Biochem./physiol. Wirkung

Methylene blue (MB) is a highly recognized histological dye. It plays a vital role in microbiology and pharmacology. It has been employed in staining living organisms and in methemoglobinemia treatment. MB exhibits maximum absorption at 664nm. Exposure to methylene blue leads to various health hazards such as increased heart rate, vomiting, shock, Heinz body formation, cyanosis, jaundice, quadriplegia and tissue necrosis in humans

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Microscopic structural alterations
and p53 immune-expression in adult
rat testis in response to intra-tunical versus
intra-parenchymal injection of methylene blue
Mazroa S A
International Journal of Clinical and Experimental Pathology, 9, 5346-5356 (2016)
Alexandru Grigoroiu et al.
Scientific reports, 10(1), 3947-3947 (2020-03-05)
Hyperspectral imaging (HSI) is being explored in endoscopy as a tool to extract biochemical information that may improve contrast for early cancer detection in the gastrointestinal tract. Motion artefacts during medical endoscopy have traditionally limited HSI application, however, recent developments
Methylene blue in photodynamic therapy: From basic mechanisms to clinical applications.
Tardivo JP
Photodiagnosis and Photodynamic Therapy, 2, 175-191 (2005)
J How et al.
Gynecologic oncology, 137(3), 436-442 (2015-04-15)
With the debate over extent of lymphadenectomy in endometrial cancer, sentinel lymph node (SLN) mapping may provide a focused approach to evaluate the most relevant lymph nodes (LN) while minimizing the complications. We evaluated SLN mapping using filtered technetium(99), indocyanine
Bram Vivijs et al.
Applied and environmental microbiology, 80(19), 6054-6061 (2014-07-27)
Some members of the family Enterobacteriaceae ferment sugars via the mixed-acid fermentation pathway. This yields large amounts of acids, causing strong and sometimes even lethal acidification of the environment. Other family members employ the 2,3-butanediol fermentation pathway, which generates comparatively

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