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Merck

04238

Sigma-Aldrich

Hydroxylapatit

puriss., meets analytical specification of Ph. Eur., BP, FCC, E341, ≥90% (calculated on glowed substance)

Synonym(e):

Calciumphosphat-hydroxid, Durapatit, Hydroxyapatit

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About This Item

Lineare Formel:
3Ca3(PO4)2 · Ca(OH)2
CAS-Nummer:
Molekulargewicht:
502.31
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.21

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Qualität

puriss.
meets analytical specification of Ph. Eur., BP, FCC, E341

Qualitätsniveau

Assay

≥90% (calculated on glowed substance)

Form

powder

Zusammensetzung

Ca, 35-40%

Verunreinigungen

residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.2% insoluble in HCl

Verlust

≤8% loss on ignition, 800 °C

Anionenspuren

chloride (Cl-): ≤1500 mg/kg
fluoride (F-): ≤50 mg/kg
sulfate (SO42-): ≤5000 mg/kg

Kationenspuren

As: ≤2 mg/kg
Cd: ≤1 mg/kg
Cu: ≤20 mg/kg
Fe: ≤400 mg/kg
Hg: ≤1 mg/kg
Pb: ≤2 mg/kg
Zn: ≤20 mg/kg

SMILES String

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChIKey

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Anwendung


  • New Physico-Chemical Analysis of Magnesium-Doped Hydroxyapatite in Dextran Matrix Nanocomposites.: This research article focuses on the development and characterization of magnesium-doped hydroxyapatite within a dextran matrix, emphasizing its potential applications in biomedical and tissue engineering fields (Predoi et al., 2023).

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Mechanical properties of sintered hydroxyapatite for prosthetic applications.
Akao M ,et al.
J. Mater. Sci., 16(3), 809-812 (1981)
P Ducheyne et al.
Biomaterials, 7(2), 97-103 (1986-03-01)
Hydroxyapatite from two sources was electrophoretically deposited onto flat titanium plate material. Depending upon the deposition conditions various changes in the structure of the ceramic were identified. A well-adhering Ti-P compound was present at the interface. Hydroxyapatite oxygenated to various
Chemical characterization of silicon-substituted hydroxyapatite
Gibson I, et al.
Journal of Biomedical Materials Research, 44(4), 422-428 (1999)
Sophie E P New et al.
Circulation research, 113(1), 72-77 (2013-04-26)
We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification. We tested the hypothesis that macrophage-derived MVs contribute
Sören Toksvig-Larsen et al.
Acta orthopaedica, 84(3), 314-318 (2013-04-30)
External fixation pins tend to loosen with time, especially from cancellous bone. A coating that releases a bisphosphonate has been shown to improve the fixation of dental implants in humans. We now tested a bisphosphonate coating on steel pins for

Questions

  1. What is the particle size of this product?

    1 answer
    1. The particle size for this product is not determined. However, other hydroxyapatite products may be of interest as the particle size is available:

      900203; Hydroxyapatite, powder, 10 μm, spec. surface area ≥80 m2/g
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/900203-BULKMKCT5305.pdf

      900204; Hydroxyapatite, powder, 5 μm, surface area ≥80 m2/g
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/900204-BULKMKCT6258.pdf

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