MABD45

Anti-DDPIV/CD26 Antibody, clone 9F1.2

clone 9F1.2, from mouse

• Synonym(e): Dipeptidyl peptidase 4, ADABP, Adenosine deaminase complexing protein 2, ADCP-2, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, CD26, Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptida
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: 9F1.2, monoclonal
• Speziesreaktivität: human
• Methode(n): western blot: suitable
• Isotyp: IgG2aκ
• NCBI-Hinterlegungsnummer: NP_001926
• UniProt-Hinterlegungsnummer: P27487
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... DPP4(1803)

Beschreibung

Allgemeine Beschreibung

Dipeptidyl peptidase 4 (EC 3.4.14.5; UniProt P27487; also known as ADABP, ADCP-2, Adenosine deaminase complexing protein 2, DPP IV, T-cell activation antigen CD26, Adenosine deaminase complexing protein 2, Dipeptidyl peptidase 4, Dipeptidylpeptidase IV, TP103) is encoded by the DPP4 (also known as CD26, ADCP2) gene (Gene ID 1803) in human. DPPIV is a homodimeric serine exopeptidase that cleaves x-proline dipeptides from the N-terminus of polypeptides. It is involved in many cellular processes such as activation of cytokines, differentiation, and cell-matrix interactions. Inhibition of DPPIV has been reported to be an effective treatment for type II diabetes. Also, DPPIV acts as a functional receptor for the newly discovered Middle East respiratory syndrome (MERS) coronavirus.

Spezifität

Reacts with both membrane-bound (MDPP) and soluble (SDPP) forms.

Immunogen

Epitope: extracellular domain

GST-tagged recombinant protein corresponding to the extracellular domain of human DDPIV/CD26.

Anwendung

Research Category
Stammzellforschung

Research Sub Category
Endothelstammzellen

This Anti-DDPIV/CD26 Antibody, clone 9F1.2 is validated for use in Western Blotting for the detection of DDPIV/CD26.

Qualität

Evaluated by Western Blotting in PC3 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected DDPIV/CD26 in 10 µg of PC3 cell lysate.

Zielbeschreibung

~100 kDa observed. Due to glycosylation, target band appears larger than the calculated molecular weight of 88.3 (MDPP) & 84.4 (SDPP) kDa Uncharacterized band(s) may appear in some lysates.

Physikalische Form

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Sonstige Hinweise

Concentration: Please refer to lot specific datasheet.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable