MAB348B

Anti-Alzheimer Precursor Protein A4 Antibody, clone 22C11, Biotin Conj. | MAB348B

clone 22C11, from mouse, biotin conjugate

• Synonym(e): Amyloid beta A4 protein, ABPP, APPI, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II, N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-amyloid protein 42, Beta
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Konjugat: biotin conjugate
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: 22C11, monoclonal
• Speziesreaktivität: rat, pig
• Speziesreaktivität (Voraussage durch Homologie): porcine (based on 100% sequence homology), mouse (based on 100% sequence homology), monkey (based on 100% sequence homology), human (based on 100% sequence homology), canine (based on 100% sequence homology)
• Methode(n): immunocytochemistry: suitable; immunohistochemistry: suitable
• Isotyp: IgG1
• NCBI-Hinterlegungsnummer: NP_000475
• UniProt-Hinterlegungsnummer: P05067
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... APP(351)

Beschreibung

Allgemeine Beschreibung

Deposits of amyloid protein in senile plaques near nerve processes are found in the brains of aged humand and cases of Alzheimer′s Disease. The principle component of this extracellular amyloid is beta A4, a 4 kDa peptide derived from a larger amyloid precursor protein (APP), which is widely expressed in the brain and body. The creation, transport and function of these proteins is currently an active area of research.

Spezifität

This antibody recognizes Alzheimer Precursor Protein A4 at the N-temrinus.

Immunogen

Epitope: N-terminus

Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein

Anwendung

Research Category
Neurowissenschaft

Research Sub Category
Neurodegenerative Krankheiten

Evaluated by Immunohistochemistry in adult rat brain tissue.

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Alzheimer Precursor Protein A4 in adult rat brain tissue.

Qualität

Evaluated by Immunocytochemistry in rat E18 primary cortex cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Alzheimer Precursor Protein A4 in rat E18 primary cortex cells.

Zielbeschreibung

Varies

Physikalische Form

Protein A purified

Purified mouse monoclonal IgG1 conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Rat E18 primary cortex cells

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable