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ABC152

Sigma-Aldrich

Anti-Annexin A2 Antibody

from rabbit, purified by affinity chromatography

Synonym(e):

Annexin A2, Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV, PAP-IV, Protein I, p36

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Antikörperform

purified antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Aufgereinigt durch

affinity chromatography

Speziesreaktivität

rat, human

Speziesreaktivität (Voraussage durch Homologie)

primate (based on 100% sequence homology), mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), porcine (based on 100% sequence homology), canine (based on 100% sequence homology)

Methode(n)

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ANXA2(302)

Allgemeine Beschreibung

Annexin A2 is known by several other names including: Annexin II, Calpactin I heavy chain, Chromobindin-8, Lipocortin II and Placental anticoagulant protein IV. Annexin A2 is a calcium-regulated membrane-binding protein that binds two calcium ions with high affinity. Annexin A2′s affinity for calcium is enhanced by anionic phospholipids. Annexin A2 has been shown to bind to human cytomegalvirus (HCMV) and may be involved in heat-stress response and apoptosis.

Spezifität

This antibody recognizes the Annexin 1 repeat domain of Annexin A2.

Immunogen

Epitope: Annexin 1 repeat domain
KLH-conjugated linear peptide corresponding to Annexin 1 repeat domain of human Annexin A2.

Anwendung

Research Category
Apoptose & Krebs
Research Sub Category
Apoptose - Weiterführende Produkte
Anti-Annexin A2 is an antibody targeting the Annexin A2 protein, validated for use in WB & IHC.
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Annexin A2 in human and rat colon tissues.

Qualität

Evaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Annexin A2 in 10 µg of A549 cell lysate.

Zielbeschreibung

~36 kDa observed

Physikalische Form

Protein A purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
A549 cell lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Shahzadi Noreen et al.
Proteomics. Clinical applications, 14(2), e1900078-e1900078 (2019-11-21)
An early and accurate diagnosis of ovarian carcinoma (OC) may reduce morbidity and mortality of the patients. To improve the clinical outcome in OC patients, the present study is aimed at identifying robust biomarkers for early OC diagnosis. EXPERIMENTAL DESIGN: In

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