8.55065
NovaSyn® TG carboxy resin
Novabiochem®
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About This Item
UNSPSC-Code:
13111023
Empfohlene Produkte
Produktlinie
NovaSyn® TG
Novabiochem®
Form
beads
Eignung der Reaktion
reaction type: Fmoc solid-phase peptide synthesis
Hersteller/Markenname
Novabiochem®
Anwendung(en)
peptide synthesis
Lagertemp.
2-30°C
Allgemeine Beschreibung
NovaSynTG carboxy resin is a composite of low cross-linked polystyrene and 3000-4000 M.W. polyethylene glycol, in which the ends of the PEG chains have been functionalized with carboxyl groups. The 130 μm beads have a narrow size distribution, high diffusion rates and excellent swelling properties across a wide range of solvents from toluene to water [1-3], making them ideally suited to the synthesis of serial and parallel libraries by organic solid phase synthesis.
This support can be used to immobilize alcohols through formation of an ester with the resin-bound carboxy group. Cleavage can be effected either by saponification, hydrazinolysis or reduction with LiBH4 .
In studies on the synthesis of furans via intramolecular radical cyclization, NovaSynTG carboxy resin was found to give superior results to carboxy polystyrene [4]. This observation was attributed to the notion that, in the PEG-based support, the radical intermediates would be prevented, by virtue of being tethered to the ends of PEG chains, from approaching and thus being quenched by the benzylic protons of the polystyrene backbone.
The product number for this product was previously 01-64-0097.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
This support can be used to immobilize alcohols through formation of an ester with the resin-bound carboxy group. Cleavage can be effected either by saponification, hydrazinolysis or reduction with LiBH4 .
In studies on the synthesis of furans via intramolecular radical cyclization, NovaSynTG carboxy resin was found to give superior results to carboxy polystyrene [4]. This observation was attributed to the notion that, in the PEG-based support, the radical intermediates would be prevented, by virtue of being tethered to the ends of PEG chains, from approaching and thus being quenched by the benzylic protons of the polystyrene backbone.
The product number for this product was previously 01-64-0097.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Verlinkung
Replaces: 01-64-0097
Hinweis zur Analyse
Farbe (visuell): weiß bis gelb bis beige
Aussehen der Substanz (visuell): Kügelchen
Beladung (Elementaranalyse aus Stickstoff nach Derivatisierung mit Methylamin): 0.30 - 0.60 mmol/g
Aufquellvolumen (in CH₂Cl₂): chargenspezifischer Wert
130 µm Kügelchen
Aussehen der Substanz (visuell): Kügelchen
Beladung (Elementaranalyse aus Stickstoff nach Derivatisierung mit Methylamin): 0.30 - 0.60 mmol/g
Aufquellvolumen (in CH₂Cl₂): chargenspezifischer Wert
130 µm Kügelchen
Rechtliche Hinweise
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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