8.52310

Fmoc-SDMA(Boc)2-ONa

Novabiochem^®

• Synonym(e): N-α-Fmoc-N,NÆ-δ-dimethyl-N,NÆ-δ-di-t.-butoxycarbonyl-L-arginine sodium salt
• Empirische Formel (Hill-System): C₃₃H₄₃N₄NaO₈
• Molekulargewicht: 646.71
• UNSPSC-Code: 12352209
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Produktlinie: Novabiochem^®
• Assay: ≥90.0% (HPLC)
• Form: powder
• Eignung der Reaktion: reaction type: Fmoc solid-phase peptide synthesis
• Hersteller/Markenname: Novabiochem^®
• Anwendung(en): peptide synthesis
• Funktionelle Gruppe: Boc; Fmoc
• Lagertemp.: -10 to -25°C

Beschreibung

Allgemeine Beschreibung

A derivative for the introduction of symmetric dimethyl-arginine during Fmoc SPPS. Coupling can be carried out using any standard activation method. Removal of the Boc protecting groups occurs during the course of the TFA-mediated cleavage reaction. Ref ^[1] contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally -Protected Building Blocks for Fmoc SPPS

Literature references

^[1] S. Rothbart, et al. (2012) Methods Enzymol., 512, 107.

Hinweis zur Analyse

Farbe (visuell): weiß bis schwach gelb bis beigestichig
Aussehen der Substanz (visuell): Pulver
Identität (IR): entspricht
Gehalt (HPLC, Fl.%): ≥ 90.0 % (a/a)
Löslichkeit (1 mmol in 2 ml DMF): klar löslich
DC-Bedingungen gemäß den Angaben unseres Hauptkataloges

Rechtliche Hinweise

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable