8.51011

MSNT

Novabiochem^®

• Synonym(e): 1-(Mesitylene-2-sulfonyl)-3-nitro-1H-1,2,4-triazole
• Empirische Formel (Hill-System): C₁₁H₁₂N₄O₄S
• CAS-Nummer: 74257-00-4
• Molekulargewicht: 296.30
• MDL-Nummer: MFCD00009754
• UNSPSC-Code: 12352005

Eigenschaften

• Produktlinie: Novabiochem^®
• Assay: ≥95.0% (HPLC)
• Form: powder
• Eignung der Reaktion: reaction type: Coupling Reactions
• Hersteller/Markenname: Novabiochem^®
• Lagertemp.: 15-25°C
• InChI: 1S/C11H12N4O4S/c1-7-4-8(2)10(9(3)5-7)20(18,19)14-6-12-11(13-14)15(16)17/h4-6H,1-3H3
• InChIKey: SFYDWLYPIXHPML-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

This versatile reagent was originally used as a coupling reagent in phosphotriester oligonucleotide synthesis [1-3]. In recent years, it has been increasingly used for the esterification of Fmoc-amino acids onto solid phase synthesis supports [4-12]. It has proved particularly effective in difficult cases involving unreactive linkers [8, 9] or enantiomerization prone amino acids [7]. In an investigation [6] into ester formation, in which the alcohol or carboxylic acid component was immobilized on a solid support, MSNT was found to give the best results of all the reagents tested (DCC, DCC/HOBt, DCC/DMAP, Ph₃P/DEAD).

The product number for this product was previously 01-62-0021.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Verlinkung

Replaces: 01-62-0021

Hinweis zur Analyse

Farbe (visuell): weiß bis schwach gelb bis beige
Aussehen der Substanz (visuell): Pulver
Identität (IR): entspricht
Gehalt (HPLC, Fl.%): ≥ 95.0 % (a/a)

Rechtliche Hinweise

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany