263275

Desmosine

A novel quaternary pyridinium poly-amino acid present in elastin.

• Synonym(e): Desmosine
• Empirische Formel (Hill-System): C₂₄H₃₉N₅O₈
• Molekulargewicht: 525.60
• UNSPSC-Code: 12352200

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥99% (TLC)
• Form: lyophilized
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; desiccated (hygroscopic); protect from light
• Löslichkeit: water: 10 mg/mL
• Versandbedingung: ambient
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

A novel quaternary pyridinium poly-amino acid present in elastin. Suggested to be responsible for the cross-linking of elastin leading to the formation of insoluble fibers. Urinary excretion of desmosine is a useful indicator of elastin breakdown resulting from increased elastase activity.

A novel quaternary pyridinium poly-amino acid present in elastin. Suggested to be responsible for the cross-linking of elastin leading to the formation of insoluble fibers. Urinary excretion of desmosine is a useful indicator of elastin breakdown resulting from increased elastase activity. Absorption max: 268 nm.

Biochem./physiol. Wirkung

Cell permeable: no

Primary Target
Cross-linking of elastin

Product does not compete with ATP.

Reversible: no

Verpackung

Packaged under inert gas

Warnhinweis

Toxicity: Standard Handling (A)

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Sonstige Hinweise

Akagawa, M., and Suyama, K. 2000. Connect. Tissue Res.41, 131.
Bode, D.C., et al. 2000. Pulm. Pharmacol. Therap.13, 175.
Viglio, S., et al. 2000. Eur. Respir. J.15, 1039.
Davis, N.R., and Anwar, R.A. 1970. J. Am. Chem. Soc.92, 3778.
Thomas, J., et al. 1963. Nature200, 651.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable