1.09888

Buffer concentrate

(borate/hydrochloric acid), traceable to SRM of NIST and PTB for 500 ml buffer solution, pH 8.00 ± 0.02 (20°C) Titrisol^®

• Synonym(e): Buffer concentrate for 500 ml buffer solution, pH 8.00 ± 0.02 (20°C)
• UNSPSC-Code: 12161705
• NACRES: NA.25

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Agentur: according to DIN 19266
• Produktlinie: Titrisol^®
• pH-Wert: 8.00 (20 °C in H₂O)
• Dichte: 1.00 g/cm³ at 20 °C
• Anwendung(en): environmental; food and beverages; general analytical; industrial qc; pharmaceutical
• Format: mixture
• Lagertemp.: 15-25°C

Beschreibung

Allgemeine Beschreibung

The Titrisol^® reference buffer concentrate [borate/hydrochloric acid; pH=8.00±0.02 (20 °C)] is analyzed in the ISO/IEC 17025 accredited calibration laboratory with a combined glass electrode and 5-point calibration according to DIN 19268 against a certified primary standard reference material following DIN 19266.

The Titrisol^® concentrated buffer material combines ease of use and maximum precision for the routine calibration and monitoring of pH instruments. To prepare the ready-to-use pH buffer solution, simply dilute the Titrisol^® buffer concentrate.

Anwendung

• Optimizing oral bioavailability in pharmaceuticals: Buffer concentrate is integral to the formulation of proniosomal drug delivery systems, as seen in the development of Irbesartan formulations where it enhances solubility and stability, facilitating improved bioavailability and therapeutic efficacy (Mujtaba et al., 2024).


• Environmental remediation: In environmental science, buffer concentrate is used to adjust the pH of solutions, ensuring optimal conditions for the mediation of electron transfers in contaminant remediation processes, particularly in treatments involving heavy metals like chromium (Li and Zhang, 2024).


• Biomedical research: Buffer concentrates are crucial for maintaining pH stability in biomedical experiments, such as studies on hemoglobin mass in response to apnea, which require precise control over biochemical conditions (Keeler et al., 2024).


• Chemical analysis: In analytical chemistry, buffer concentrates are used to stabilize the environment during the voltammetric determination of dyes, ensuring accuracy and repeatability in the detection of chemical substances (Moulya et al., 2024).

Leistungsmerkmale und Vorteile

• Traceable to primary standard reference materials from NIST and PTB
• Analytical standard Grade
• Uncertainty data and traceability are documented in a comprehensive and batch-specific Certificate of Analysis.

Hinweis zur Analyse

pH-Wert (20 °C): 8,00 ± 0,02
Gemessen nach dem Auffüllen auf 500 ml mit einer kombinierten Glaselektrode nach Mehrpunktkalibration (nach DIN 19268) mit Referenzmaterialien zur Herstellung von Standardpufferlösungen nach DIN 19266.

Rechtliche Hinweise

Titrisol is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H360FD
• P-Sätze: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Repr. 1B
• Lagerklassenschlüssel: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable