07-1407

Anti-GLUT-8 Antibody, CT

from rabbit

• Synonym(e): Glucose transporter type 8, Glucose transporter type X1, glucose transporter X1, solute carrier family 2 (facilitated glucose transporter) ; ; member 8, solute carrier family 2 (facilitated glucose transporter), ; ; member 8
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Speziesreaktivität: human
• Speziesreaktivität (Voraussage durch Homologie): mouse
• Methode(n): immunohistochemistry: suitable (paraffin)
• UniProt-Hinterlegungsnummer: Q9NY64
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... SLC2A8(29988) ; mouse ... Slc2A8(56017)

Beschreibung

Allgemeine Beschreibung

GLUT-8 is a glucose transporter facilitated by the regulation of insulin, binding cytochalasin B such that the orientation is glucose-inhibitive. In appearance, the transporter seems to be a dual-specific sugar transporter since fructose can also be inhibitive. GLUT-8 is expressed largely in the testis, where down-regulation is facilitated by estrogen. However, GLUT-8 is not highly expressed in testicular carcinoma. Lower levels of GLUT-8 are present in most other tissues.

Spezifität

Recognizes GLUT-8.

Immunogen

An 11 amino acid sequence near the C-terminus of mouse Glut-8 (Doege et al. 2000; Carayannopoulos et al. 2000)

Epitope: C-terminus

Anwendung

Research Category
Zelluläre Signaltransduktion

Research Sub Category
Insulin-/stoffwechselassoziierte Signalübertragung

Anti-GLUT-8 Antibody, C-terminus detects level of GLUT-8 & has been published & validated for use in IH(P).

Qualität

Evaluated by Immunohistochemistry in human kidney tissue
Immunohistochemistry Analysis: 1:100 dilution of this lot detected GLUT-8 in human kidney tissue.

Zielbeschreibung

Approx. 50 kDa

Verlinkung

Replaces: AB3140

Physikalische Form

ImmunoAffinity Purified

Format: Purified

Liquid in PBS with 0.1% BSA.

Lagerung und Haltbarkeit

Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.

Hinweis zur Analyse

Control
Human kidney tissue.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable