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Merck
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Wichtige Dokumente

06-559

Sigma-Aldrich

Anti-Pyk2 Antibody

Upstate®, from rabbit

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human, mouse

Hersteller/Markenname

Upstate®

Methode(n)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

NM_173174

UniProt-Hinterlegungsnummer

Q14289

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... PTK2B(2185)

Spezifität

Recognizes Pyk2, and its degradation products; does not cross-react with FAK.

Immunogen

GST-fusion protein containing amino acids 726-863 of human Pyk2

Anwendung

Research Category
Zelluläre Signaltransduktion
Research Sub Category
Cytoskelettale Signalübertragung
This Anti-Pyk2 Antibody is validated for use in IC, IP, WB for the detection of Pyk2.

Qualität

routinely evaluated by immunoblot on mouse brain cytosolic RIPA lysates

Zielbeschreibung

125 kDa

Physikalische Form

Protein A purified
Format: Purified
Protein A Purified immunoglobulin in 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Mouse brain cytosolic RIPA lysates

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Archives of Otolaryngology--Head & Neck Surgery null
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Cancer communications (London, England), 42(11), 1185-1206 (2022-08-31)
Multiple myeloma (MM) is the second most common hematological malignancy. An overwhelming majority of patients with MM progress to serious osteolytic bone disease. Aminoacyl-tRNA synthetase-interacting multifunctional protein 1 (AIMP1) participates in several steps during cancer development and osteoclast differentiation. This
Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival.
Ssang-Taek Lim,Nichol L G Miller,Ju-Ock Nam,Xiao Lei Chen,Yangmi Lim,David D Schlaepfer
The Journal of Biological Chemistry null
Shinichi Nakano et al.
Scientific reports, 9(1), 4236-4236 (2019-03-14)
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Hydroxamic acid derivatives of mycophenolic acid inhibit histone deacetylase at the cellular level.
Daniela I Batovska,Dong Hoon Kim,Shinya Mitsuhashi,Yoon Sun Cho,Ho Jeong Kwon,Makoto Ubukata
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