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T-904

Supelco

Trimipramine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirische Formel (Hill-System):
C20H26N2
CAS-Nummer:
739-71-9
Molekulargewicht:
294.43
MDL-Nummer:
MFCD00242595
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329826892
NACRES:
NA.24

Qualität

certified reference material

Form

liquid

Leistungsmerkmale

Snap-N-Spike®/Snap-N-Shoot®

Verpackung

ampule of 1 mL

Hersteller/Markenname

Cerilliant®

Konzentration

1.0 mg/mL in methanol

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Anwendung(en)

clinical testing

Format

single component solution

Lagertemp.

2-8°C

SMILES String

CN(C)CC(C)CN1C2=C(C=CC=C2)CCC3=C1C=CC=C3

InChI

1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3

InChIKey

ZSCDBOWYZJWBIY-UHFFFAOYSA-N

Angaben zum Gen

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , DRD2(1813) , HRH1(3269) , HTR2A(3356) , HTR2C(3358) , SLC6A2(6530)

Allgemeine Beschreibung

Trimipramine is a tricyclic antidepressant prescribed for treatment of depression, insomnia, and chronic pain or as an adjunctive therapy for alcohol or opioid withdrawal. This certified solution standard is applicable for use in clinical toxicology, forensic analysis, or urine drug testing applications by LC-MS/MS or GC/MS. Trimipramine is marketed under the trade names Surmontil®, Rhotrimine, and Stangyl.

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Surmontil is a registered trademark of Pliva, Inc.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Zielorgane

Eyes,Central nervous system

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

49.5 °F - closed cup

Flammpunkt (°C)

9.7 °C - closed cup

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Donald F Smith et al.
Psychopharmacology, 195(1), 131-138 (2007-07-27)
Molecular tools are needed for assessing anti-depressant actions by positron emission tomography (PET) in the living human brain. This study determined whether [(11)C]mirtazapine is an appropriate molecular tool for use with PET to estimate the magnitude of neuroreceptor occupancy produced
Britta Haenisch et al.
Psychopharmacology, 217(2), 289-295 (2011-04-13)
The antidepressant trimipramine shows an atypical pharmacological profile and its mechanism of action is still obscure. The present study investigated whether trimipramine and three of its metabolites interact with targets of other antidepressants, namely, the human monoamine transporters for noradrenaline
Yusuf Oztürk et al.
Pharmacology, biochemistry, and behavior, 83(4), 592-597 (2006-05-23)
The present study was designed to investigate the involvement of endogenous opioid systems in the antinociception induced by the antidepressant drugs, desipramine and trimipramine. For this purpose, the antinociceptive effects of desipramine (7.5 and 15.0 mg/kg i.p.) and trimipramine (5.0
Ali R Fakhari et al.
Electrophoresis, 33(3), 506-515 (2012-01-31)
A sensitive, simple and reproducible method was developed for preconcentration and determination of trimipramine (TPM) enantiomers in biological samples using electromembrane extraction combined with cyclodextrin-modified capillary electrophoresis (CE). During the extraction, TPM enantiomers migrated from a 5 mL sample solution through
Diansong Zhou et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(5), 863-870 (2010-02-06)
The role of human UDP glucuronosyltransferase (UGT) 2B10 in the N-glucuronidation of a number of tricyclic antidepressants was investigated and compared with that of UGT1A4 in both the Sf9 expressed system and human liver microsomes. The apparent K(m) (S(50)) values
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