860521P

C16 Galactosyl(β) Ceramide (d18:1/16:0)

Avanti Research^™ - A Croda Brand 860521P, powder

• Synonym(e): D-galactosyl-β-1,1′ N-palmitoyl-D-erythro-sphingosine
• Empirische Formel (Hill-System): C₄₀H₇₇NO₈
• CAS-Nummer: 34324-89-5
• Molekulargewicht: 700.04
• MDL-Nummer: MFCD00955532
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Form: powder
• Verpackung: pkg of 1 × 5 mg (860521P-5mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 860521P
• Lipid-Typ: sphingolipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O
• InChI: 1S/C40H77NO8/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(43)33(32-48-40-39(47)38(46)37(45)35(31-42)49-40)41-36(44)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,33-35,37-40,42-43,45-47H,3-26,28,30-32H2,1-2H3,(H,41,44)/b29-27+/t33?,34-,35-,37+,38+,39-,40+/m1/s1
• InChIKey: VJLLLMIZEJJZTE-BUDJNAOESA-N

Beschreibung

Allgemeine Beschreibung

D-galactosyl-β-1,1′N-palmitoyl-D-erythro-sphingosine or C16 Galactosyl(β) ceramide consists of a cer(d18:1/16:0) core structure to which a sugar molecule and galactose, is linked through β-glycosidic linkage.[1] Galactosyl ceramide is a complex glycosphingolipid,[2] which contains a single galactose residue linked to ceramide.[3] It is a major constituent of the myelin sheath.[2] Galactosyl ceramide is found majorly on the surface of colonic epithelial cells, vaginal epithelium and primary mammary epithelial cells.[4]

Anwendung

C16 Galactosyl(β) ceramide (d18:1/16:0) has been used as a lipid standard for its quantification using differential ion mobility spectrometry (DMS) coupled with liquid chromatography in electrospray ionization tandem mass spectrometry (LC-ESI-DMS-MS/MS) in human plasma.[1] It has also been used for the preparation of lipid dispersions.[5] It may be used as a glycosphingolipid (GSL) standard to optimize its characteristic fragmentation using electrospray ionization (ESI) triple quadrupole tandem mass spectrometry (MS/MS).[6] It may also be used to study the structural changes caused by ultraviolet (UVA)?induced photooxidation of galactosyl (GalCer) by electrospray ionization mass spectrometry (ESI?MS) analysis.[7]

Biochem./physiol. Wirkung

Galactosyl ceramide is crucial for normal myelin function and stability.[8] It prevents epithelial cell-human immunodeficiency virus 1 (HIV-1) virion binding.[4]

Verpackung

5 mL Amber Glass Screw Cap Vial (860521P-5mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable