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850182P

Avanti

08:0 PI(4)P

Avanti Research - A Croda Brand

Synonym(e):

PIP[4′](8:0/8:0)

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100 μG
CHF 185.00
500 μG
CHF 739.00

CHF 185.00


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100 μG
CHF 185.00
500 μG
CHF 739.00

About This Item

Empirische Formel (Hill-System):
C25H54N2O16P2
CAS-Nummer:
Molekulargewicht:
700.65
MDL-Nummer:
UNSPSC-Code:
51191904
NACRES:
NA.25

CHF 185.00


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Beschreibung

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′-phosphate) (ammonium salt)

Assay

>99% (TLC)

Form

powder

Verpackung

pkg of 1 × 100 μg (with stopper and crimp cap (850182P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850182P-500ug))

Hersteller/Markenname

Avanti Research - A Croda Brand

Lipid-Typ

phospholipids
cardiolipins

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C25H48O16P2.2H3N/c1-3-5-7-9-11-13-18(26)37-15-17(39-19(27)14-12-10-8-6-4-2)16-38-43(35,36)41-25-22(30)20(28)24(21(29)23(25)31)40-42(32,33)34;;/h17,20-25,28-31H,3-16H2,1-2H3,(H,35,36)(H2,32,33,34);2*1H3/t17-,20-,21+,22-,23-,24+,25+;;/m1../s1

InChIKey

GRYUDEZZGXKOJR-JHABFHEXSA-N

Allgemeine Beschreibung

08:0 PI[1]P is a phosphoinositol phosphate (PIP).[2] Among prokaryotes, PI is synthesized by mycobacteria and few other bacterial genera.[3]
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Anwendung

08:0 PI[1]P has been used to prepare multilamellar vesicle liposomes (MLV) for lipid binding assays.[1] It is also suitable for use in the formation of protein-lipid tube[4] and to examine fluorescence spectrum for analysing the PI[1]P/sterol exchange properties of the Osh1 OSBP-related domain (ORD)[5]

Biochem./physiol. Wirkung

08:0 PI[1]P can control ion channel activity. Phosphoinositol phosphates (PIPs) with short acyl chains, that are soluble in water can be used for reversible transport into the plasma membrane.[2]

Verpackung

2 mL Amber Serum Vial with Stopper and Crimp Cap (850182P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850182P-500ug)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

No data available

Flammpunkt (°C)

No data available


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Analysenzertifikate (COA)

Lot/Batch Number

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

An endophilin-dynamin complex promotes budding of clathrin-coated vesicles during synaptic vesicle recycling
Sundborger A, et al.
Journal of Cell Science, 124(1), 133-143 (2011)
Intracellular traffic of the lysine and glutamic acid rich protein KERP1 reveals features of endomembrane organization in Entamoeba histolytica
Perdomo D, et al.
Cellular Microbiology, 18(8), 1134-1152 (2016)
Structure of yeast OSBP-related protein Osh1 reveals key determinants for lipid transport and protein targeting at the nucleus-vacuole junction
Manik MK, et al.
Structure, 25(4), 617-629 (2017)
Short-chain phosphoinositide partitioning into plasma membrane models
Collins MD and Gordon SE
Biophysical Journal, 105(11), 2485-2494 (2013)
Ke Wang et al.
The Journal of biological chemistry, 287(45), 37964-37972 (2012-09-15)
Macroautophagy (hereafter autophagy) is a degradative cellular pathway that protects eukaryotic cells from stress, starvation, and microbial infection. This process must be tightly controlled because too little or too much autophagy can be deleterious to cellular physiology. The phosphatidylinositol (PtdIns)

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