810314P

NBD Phytosphingosine

Omega-NBD D-ribo-Phytosphingosine, powder

• Synonym(e): (2S,3S,4R)-2-amino-18-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)octadecane-1,3,4-triol
• Empirische Formel (Hill-System): C₂₄H₄₁N₅O₆
• CAS-Nummer: 2260669-58-5
• Molekulargewicht: 495.61
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 100 μg (810314P-100ug); pkg of 1 × 250 μg (810314P-250ug); pkg of 1 × 50 μg (810314P-50ug)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 810314P
• Versandbedingung: dry ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Phytosphingosine (PHS) is one of the important constituent of phytoceramides. This sphingoid has a hydroxyl group at C-4 of the sphingoid long-chain base. PHS is a component of mammalian epidermis and is widely distributed in fungi and plants. Nitrobenzoxadiazole/7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) is a fluorescent conjugate.

Anwendung

NBD Phytosphingosine has been used as a substrate in ceramide synthase assays.

Biochem./physiol. Wirkung

Phytosphingosine (PHS) is capable of activating G-protein coupled receptor 120 (GPR120). Treating cultured keratinocytes (KC) with PHS can enhance the content of ceramide NP. It plays as key role in epidermal differentiation and also possesses anti-inflammatory and antimicrobial activities.

Verpackung

5 mL Amber Glass Screw Cap Vial (810314P-100ug)

5 mL Amber Glass Screw Cap Vial (810314P-250ug)

5 mL Amber Glass Screw Cap Vial (810314P-50ug)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3