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790304P

Avanti

Coag Reagent I

Avanti Research™ - A Croda Brand 790304P, powder

Synonym(e):

Coag Reagent, Coagulation Reagent I, contains DOPE:DOPS:DOPC (5:3:2 w/w)

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About This Item

UNSPSC-Code:
12352211
NACRES:
NA.25

Form

powder

Verpackung

pkg of 2 × 100 mg (790304P-200mg)
pkg of 1 × 25 mg (790304P-25mg)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 790304P

Anwendung(en)

microbiology

Lipid-Typ

phospholipids

Versandbedingung

dry ice

Lagertemp.

−20°C

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Allgemeine Beschreibung

Coag Reagent I comprises 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (DOPS) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) in the ratio 5:3:2 w/w. They are present predominantly in the synaptic vesicle membrane. DOPC has choline group and DOPE comprises ethanolamine moiety. At neutral pH, DOPE and DOPC exist as a zwitterion whereas DOPS takes up a negative charge and has a serine group.

Anwendung

Coag Reagent I has been used in the preparation of small unilamellar vesicles (SUVs) for α-synuclein binding studies. It may be used in the preparation of bilayers for reconstituting ryanodine receptor type 2 (RyR2) for single-channel recording studies. It may be used for glass supported lipid bilayers preparation.

Biochem./physiol. Wirkung

Coag Reagent I mixed lipid is useful in the preparation of supported lipid bilayers and platelet membranes for coagulation studies. It is used in the small unilamellar vesicles (SUVs) generation for α-synuclein and squalamine binding studies.

Verpackung

5 mL Clear Glass Sealed Ampule (790304P-200mg)
5 mL Clear Glass Sealed Ampule (790304P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

No data available

Flammpunkt (°C)

No data available

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

A natural product inhibits the initiation of alpha-synuclein aggregation and suppresses its toxicity
Perni M, et al.
Proceedings of the National Academy of Sciences of the USA, 114(6), E1009-E1017 (2017)
EL20, a potent antiarrhythmic compound, selectively inhibits calmodulin-deficient ryanodine receptor type 2
Klipp RC, et al.
Heart Rhythm : the Official Journal of the Heart Rhythm Society, 15(4), 578-586 (2018)
A M van den Besselaar et al.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 4(6), 895-903 (1993-12-01)
The activated partial thromboplastin time (aPTT) is the most popular test for monitoring of heparin therapy. The purpose of the present study was to show that an aPTT reagent with good response to heparin can be prepared from synthetic phosphoglycerides.
Nuclear magnetic resonance observation of ?-synuclein membrane interaction by monitoring the acetylation reactivity of its lysine side chains
Lee JH, et al.
Biochemistry, 55(35), 4949-4959 (2016)
Three-Dimensional Heterogeneous Structure Formation on a Supported Lipid Bilayer Disclosed by Single-Particle Tracking
Zhong Y & Wang G
Langmuir, 34(39), 11857-11865 (2018)
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