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Merck

D7927

Sigma-Aldrich

Sinapinsäure

≥98%, powder

Synonym(e):

3,5-Dimethoxy-4-hydroxyzimtsäure, 4-Hydroxy-3,5-dimethoxy-zimtsäure

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1 G
CHF 62.90
5 G
CHF 171.00

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1 G
CHF 62.90
5 G
CHF 171.00

About This Item

Empirische Formel (Hill-System):
C11H12O5
CAS-Nummer:
Molekulargewicht:
224.21
Beilstein:
2699118
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22

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Assay

≥98%

Form

powder

Mol-Gew.

monoisotopic mol wt 224.06839 Da

mp (Schmelzpunkt)

~202 °C

Löslichkeit

H2O: slightly soluble (lit.)(lit.)
methanol: water: soluble (lit.)(lit.)
polar organic solvents: soluble (lit.)(lit.)

SMILES String

COc1cc(\C=C\C(O)=O)cc(OC)c1O

InChI

1S/C11H12O5/c1-15-8-5-7(3-4-10(12)13)6-9(16-2)11(8)14/h3-6,14H,1-2H3,(H,12,13)/b4-3+

InChIKey

PCMORTLOPMLEFB-ONEGZZNKSA-N

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Allgemeine Beschreibung

Sinapic acid is an hydroxycinnamic acid derivative that occurs naturally in Brassicaceae species [1] [2].

Sinapic acid is a phenylpropanoid derivative that acts as a radical scavenger with antioxidant, antimicrobial, anti-inflammatory, and anticancer properties. [3]

Anwendung

Sinapic acid can be used:
  • As a potent peroxynitrite (ONOO−) oxidant scavenger for the protection of the cellular constituents against peroxynitrite cytotoxic species.[1]
  • In the synthesis of antioxidant hydroxycinnamic acid xylan esters via esterification reaction.[4]
  • In the synthesis of pseudo-cinnamic derivatives effective against mycobacterium tuberculosis.[5]

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Sinapic acid: is it safe for humans?
Hasan H et al.
FABAD Journal of Pharmaceutical Sciences, 41, 39-39 (2016)
Synthesis and antioxidant activity of hydroxycinnamic acid xylan esters.
Wrigstedt P, et al.
Journal of Agricultural and Food Chemistry, 58(11), 6937-6943 (2010)
Peroxynitrite scavenging activity of sinapic acid (3, 5-dimethoxy-4-hydroxycinnamic acid) isolated from Brassica juncea.
Zou Y, et al.
Journal of Agricultural and Food Chemistry, 50(21), 5884-5890 (2002)
Sinapic acid and its derivatives: natural sources and bioactivity.
Niciforovic N and Abramovivc H
Comprehensive Reviews in Food Science and Food Safety, 13(1), 34-51 (2014)
Urska Repnik et al.
The Journal of biological chemistry, 290(22), 13800-13811 (2015-04-03)
Cysteine cathepsins are primarily lysosomal proteases involved in general protein turnover, but they also have specific proteolytic functions in antigen presentation and bone remodeling. Cathepsins are most stable at acidic pH, although growing evidence indicates that they have physiologically relevant

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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