ALD00594

2-Hydroxynicotinaldehyde

97%

• Synonym(e): 2-Hydroxy-pyridine-3-carbaldehyde, TDG4
• Empirische Formel (Hill-System): C₆H₅NO₂
• CAS-Nummer: 36404-89-4
• Molekulargewicht: 123.11
• MDL-Nummer: MFCD09909918
• UNSPSC-Code: 12352200
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Form: powder or crystals
• Eignung der Reaktion: reaction type: C-C Bond Formation; reagent type: catalyst; reagent type: ligand; reaction type: C-H Activation
• mp (Schmelzpunkt): 223 °C
• Funktionelle Gruppe: aldehyde
• Lagertemp.: 2-8°C
• InChI: 1S/C6H5NO2/c8-4-5-2-1-3-7-6(5)9/h1-4H,(H,7,9)
• InChIKey: DNTYEVWEOFZXFE-UHFFFAOYSA-N

Beschreibung

Anwendung

This reagent was used as a catalytic transient directing group by Jin-Quan Yu′s lab for Pd(II)-catalyzed γ-C(sp³)-H arylation to couple free primary amines with aryl iodides. Reactions included Pd(OAc)₂ 683124 and low catalyst and directing group loading.

Quellenangabe

Pd-Catalyzed γ-C(sp³)-H Arylation of Free Amines Using a Transient Directing Group

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable