The molecular weight is not determined, however the specification for Brookfield viscosity is 8 - 14 cP at 5% in water, 25°C. The term “low molecular weight ” refers to the raw material polymer used to manufacture this material.
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Trimethyl chitosan
low molecular weight, degree of quaternization >50%
Synonym(e):
N,N,N-Trimethyl chitosan, Chitosan trimethyl, Mucoadhesive polymers, TMC Chitosan
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1 G
CHF 387.00
About This Item
Lineare Formel:
(C9H18ClNO4)n
CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352201
NACRES:
NA.23
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Anwendung
Chitosan offers remarkable biological properties, it has been widely used in drug delivery and tissue engineering applications. Chitosan has good mucoadhesive properties due to its positive charge, which increases the adhesion to mucosa and facilitates drug penetration. Also, chitosan possesses hemostatic properties, which makes it a good candidate for wound dressing applications.
The quaternization of the primary amine increases the water solubility of chitosan and keeps chitosan soluble over a wide pH range. Among all the quaternized chitosans, N, N, N-trimethyl chitosan chloride (TMC) is the most widely applied in biomedical applications.
The quaternization of the primary amine increases the water solubility of chitosan and keeps chitosan soluble over a wide pH range. Among all the quaternized chitosans, N, N, N-trimethyl chitosan chloride (TMC) is the most widely applied in biomedical applications.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Preparation and Characterization of Particles from Chitosan with Different Molecular Weights and Their Trimethyl Chitosan Derivatives for Nasal Immunization.
Boonyo W, et al.
The Journal of The Minerals, Metals & Materials Society, 18(2), 59-65 (2008)
Preparation and NMR characterization of highly substituted IV-trimethyl chitosan chloride.
Sieval A B, et al.
Carbohydrate Polymers, 36, 157-165 (1998)
Chitosan and Chitosan Derivatives in Drug Delivery and Tissue Engineering.
Riva R, et al.
Advances in Polymer Science, 244, 19-44 (2011)
J H Hamman et al.
Drug development and industrial pharmacy, 29(2), 161-172 (2003-03-22)
N-trimethyl chitosan chloride (TMC) is a polycation that enhances drug transport across epithelia by opening tight junctions. The degree of quaternization of TMC determines the number of positive charges available on the molecule for interactions with the negatively charged sites
Amir K Varkouhi et al.
Bioconjugate chemistry, 21(12), 2339-2346 (2010-11-06)
N,N,N-Trimethylated chitosan (TMC) is a biodegradable polymer emerging as a promising nonviral vector for nucleic acid and protein delivery. In the present study, we investigated whether the introduction of thiol groups in TMC enhances the extracellular stability of the complexes
Artikel
Professor Robert K. Prud’homme introduces flash nanoprecipitation (FNP) for nanoparticle fabrication, which is a scalable, rapid mixing process for nanoparticle formulations.
Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.
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Hi! We ordered and received this product, but we were inquiring to see if we could also get an exact molecular weight of this product as well. Thank you!
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