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730971

Sigma-Aldrich

2-(Diisopropylamino)ethylmethacrylat

97%, contains ~100 ppm monomethyl ether hydroquinone as inhibitor

Synonym(e):

DPA, DPAEMA

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25 G
CHF 98.00
100 G
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About This Item

Empirische Formel (Hill-System):
C12H23NO2
CAS-Nummer:
Molekulargewicht:
213.32
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12162002
PubChem Substanz-ID:
NACRES:
NA.23

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Qualitätsniveau

Assay

97%

Form

liquid

Enthält

~100 ppm monomethyl ether hydroquinone as inhibitor

Brechungsindex

n20/D 1.145

Dichte

0.900 g/mL at 25 °C

Lagertemp.

2-8°C

SMILES String

CC(C)N(CCOC(=O)C(C)=C)C(C)C

InChI

1S/C12H23NO2/c1-9(2)12(14)15-8-7-13(10(3)4)11(5)6/h10-11H,1,7-8H2,2-6H3

InChIKey

SVYHMICYJHWXIN-UHFFFAOYSA-N

Allgemeine Beschreibung

2-(Diisopropylamino)ethyl methacrylate (DPA) is a methacrylate class of monomer used to prepare various DPA-derived polymers, which includes poly(2-(diisopropylamino)ethyl methacrylate) (PDPA). PDPA is a water-soluble polymer, which exhibits sensitivity to changes in pH and temperature. At pH levels below its pKa value of approximately 6.5, PDPA undergoes a transition from hydrophobic to hydrophilic behavior. This transition is attributed to the protonation of its amino groups. These unique properties of PDPA polymers consequently make them very useful in various applications such as drug delivery, gene delivery, sensors, surfaces, membranes, and chromatography.[1][2]

Anwendung

2-(Diisopropylamino)ethyl methacrylate can be used:
  • As a monomer in the synthesis of multi-responsive hyperbranched copolymers by combining poly(oligo(ethylene glycol)methyl methacrylate) (P(OEGMA)) and 2-(diisopropylamino)ethyl methacrylate (PDIPAEMA) using RAFT polymerization. These polymers find application in drug delivery, gene delivery and tissue engineering.
  • A monomers in the synthesis of block copolymer poly(ethyleneglycol)-b-poly(2-(diisopropylamino)ethyl methacrylate) (PEG-b-PDPAEMA). These pH-responsive micelles can be used for enhanced intracellular drug delivery. The DPA monomer contributes to the pH-responsive nature of the copolymers.

Piktogramme

CorrosionExclamation mark

Signalwort

Danger

Gefahreneinstufungen

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

210.0 °F

Flammpunkt (°C)

98.9 °C


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