685860

(1R,2R)-1,2-Bis(2-hydroxyphenyl)ethylendiamin

95% (HPLC)

• Synonym(e): (1R,2R)-1,2-Bis-(2-hydroxyphenyl)-1,2-ethandiamin
• Empirische Formel (Hill-System): C₁₄H₁₆N₂O₂
• CAS-Nummer: 870991-70-1
• Molekulargewicht: 244.29
• MDL-Nummer: MFCD09751760
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 24885846
• NACRES: NA.22

Eigenschaften

• Assay: 95% (HPLC)
• Form: powder
• Optische Aktivität: [α]22/D +62°, c = 1% in chloroform
• mp (Schmelzpunkt): 157-163 °C
• Funktionelle Gruppe: amine
• SMILES String: N[C@@H]([C@H](N)c1ccccc1O)c2ccccc2O
• InChI: 1S/C14H16N2O2/c15-13(9-5-1-3-7-11(9)17)14(16)10-6-2-4-8-12(10)18/h1-8,13-14,17-18H,15-16H2/t13-,14-/m1/s1
• InChIKey: MRNPLGLZBUDMRE-ZIAGYGMSSA-N

Beschreibung

Allgemeine Beschreibung

(1R, 2R)-1,2-Bis(2-hydroxyphenyl)ethylenediamine or (R, R)-1,2-bis(2-hydroxyphenyl)-1,2-diaminoethane (HPEN) is commonly used in the stereoselective synthesis of enantiopure compounds.

Anwendung

(1R, 2R)-1,2-Bis(2-hydroxyphenyl)ethylenediamine can be used as a precursor for the synthesis of:

• Enantiomerically pure trans-3-arylpiperazine-2-carboxylic acid derivatives via diaza-Cope rearrangement (DCR).
• 4,4′-(1,2-Diazaniumylethane-1,2-diyl)dibenzoate trihydrate by treating with terephthalaldehydic acid.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves