68193

L-3-Phenyl-milchsäure-methylester

≥97.0% (HPLC)

• Synonym(e): (S)-2-Hydroxy-3-phenyl-propionsäure-methylester
• Empirische Formel (Hill-System): C₁₀H₁₂O₃
• CAS-Nummer: 13673-95-5
• Molekulargewicht: 180.20
• MDL-Nummer: MFCD00038224
• UNSPSC-Code: 12352108
• PubChem Substanz-ID: 57652130
• NACRES: NA.22

Eigenschaften

• Assay: ≥97.0% (HPLC)
• Optische Aktivität: [α]/D +4.4±0.5°, c = 1% in methanol
• mp (Schmelzpunkt): 40-45 °C (lit.)
• Funktionelle Gruppe: ester; hydroxyl; phenyl
• SMILES String: COC(=O)[C@@H](O)Cc1ccccc1
• InChI: 1S/C10H12O3/c1-13-10(12)9(11)7-8-5-3-2-4-6-8/h2-6,9,11H,7H2,1H3/t9-/m0/s1
• InChIKey: NMPPJJIBQQCOOI-VIFPVBQESA-N

Beschreibung

Anwendung

Methyl L-3-phenyllactate can be used:

• As an intermediate in the synthesis of bortezomib analogs as 20S proteasome inhibitors.
• As a substrate in the amination of the benzylic C-H bonds and the aminated products are further used to prepare β-lactams.
• As an intermediate in one of the key synthetic steps for the preparation of YM-254890 analog, a selective Gαq/11 inhibitor.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)