549762

6,8-Dichloroctansäure-ethylester

95%

• Lineare Formel: CH₃CH₂OCO(CH₂)₄CH(Cl)(CH₂)₂Cl
• CAS-Nummer: 1070-64-0
• Molekulargewicht: 241.15
• EG-Nummer: 435-080-1
• MDL-Nummer: MFCD01711127
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24874721

Eigenschaften

• Assay: 95%
• Brechungsindex: n20/D 1.462 (lit.)
• Dichte: 1.107 g/mL at 25 °C (lit.)
• SMILES String: CCOC(=O)CCCCC(Cl)CCCl
• InChI: 1S/C10H18Cl2O2/c1-2-14-10(13)6-4-3-5-9(12)7-8-11/h9H,2-8H2,1H3
• InChIKey: RFYDWSNYTVVKBR-UHFFFAOYSA-N

Beschreibung

Anwendung

Ethyl 6,8-dichlorooctanoate may be used as a starting material in the synthesis of 6-selenolipoic acid and α-lipoic acid derivatives, which show potent anticancer activity.
It may also be used as a starting material to synthesize:

• 6,8-Dibenzylmercaptooctanoic acid, an intermediate for the preparation of DL-α-lipoic acid.
• Ethyl 5,7-dichloroheptanoate, an intermediate for the preparation of DL-1,2-dithiolane-3-butyric acid.
• 7-Bromo-1,3-dichloroheptane, an intermediate for the preparation of DL-12-dithiolane-3-butanesulfonamide.

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H317,H411
• P-Sätze: P273 - P280 - P302 + P352
• Gefahreneinstufungen: Aquatic Chronic 2 - Skin Sens. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): 230.0 °F - closed cup
• Flammpunkt (°C): 110 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter