Direkt zum Inhalt
Merck
Alle Fotos(3)

Wichtige Dokumente

Gesamtdokumentation anzeigen

465119

Sigma-Aldrich

Baicalein

98%

Synonym(e):

5,6,7-Trihydroxy-flavon

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Größe auswählen

100 MG
CHF 45.30
500 MG
CHF 143.00

CHF 45.30

Check Cart for Availability
Bulk-Bestellung anfordern
Alle Fotos(3)

Größe auswählen

Ansicht ändern
100 MG
CHF 45.30
500 MG
CHF 143.00

About This Item

Empirische Formel (Hill-System):
C15H10O5
CAS-Nummer:
491-67-8
Molekulargewicht:
270.24
Beilstein:
272683
MDL-Nummer:
MFCD00017459
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24870246
NACRES:
NA.22

CHF 45.30

Check Cart for Availability
Bulk-Bestellung anfordern

Qualitätsniveau

100

Assay

98%

Form

solid

mp (Schmelzpunkt)

256-271 °C (lit.)

Funktionelle Gruppe

ketone
phenyl

SMILES String

Oc1cc2OC(=CC(=O)c2c(O)c1O)c3ccccc3

InChI

1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H

InChIKey

FXNFHKRTJBSTCS-UHFFFAOYSA-N

Angaben zum Gen

mouse ... Hexa(15211)
rat ... Alox15(81639) , Alox5(25290)

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Verwandte Kategorien

Allgemeine Beschreibung

Baicalein, a flavonoid, is a xanthine oxidase inhibitor.[1] Anti-inflammatory effects of baicalein in peripheral human leukocytes has been studied.[2]

Anwendung

Baicalein was used in a study to investigate the in vitro quantitative inhibition of lipoxygenase.[3]

Biochem./physiol. Wirkung

The flavonoid component of Nepalese and Sino-Japanese crude drugs.[4][5] Baicalein, a major flavone of Scutellariae baicalensis, inhibits the 12-lipoxygenase (12-LOX) pathway of arachidonic acid metabolism, which inhibits cancer cell proliferation and induces apoptosis.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
MKCX1335
MKCR0734
0000239789
0000195123
MKCS3854

Die passende Version wird nicht angezeigt?

Wenn Sie eine bestimmte Version benötigen, können Sie anhand der Lot- oder Chargennummer nach einem spezifischen Zertifikat suchen.

Suche nach COA

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Kunden haben sich ebenfalls angesehen

Slide 1 of 4

1 of 4

Candidone ≥95% (LC/MS-ELSD)

Sigma-Aldrich

SMB00135

Candidone

Scutellarein ≥98% (HPLC)

Sigma-Aldrich

S0327

Scutellarein

Chrysin ≥96.5%

Sigma-Aldrich

C80105

Chrysin

Wogonin hydrate ≥98% (HPLC), solid

Sigma-Aldrich

W0769

Wogonin hydrate

Wujun Dong et al.
Acta pharmaceutica Sinica. B, 10(8), 1576-1585 (2020-09-24)
Efficient mucosal delivery remains a major challenge for the reason of the respiratory tract mucus act as a formidable barrier to nanocarriers by trapping and clearing foreign particulates. The surface property of nanoparticles determines their retention and penetration ability within
Wei-Tien Chang et al.
The American journal of Chinese medicine, 41(2), 315-331 (2013-04-04)
Previous studies suggest baicalein, in addition to its antioxidant effects, protects against hypoxia/reoxygenation injury via its pro-oxidant properties. We hypothesize that a brief period of baicalein treatment prior to ischemia/reperfusion (I/R) may trigger preconditioning protection via a mitochondrial pro-oxidant mechanism.
Naheed Riaz et al.
Phytochemistry, 65(8), 1129-1135 (2004-04-28)
Paeoninol and paeonin C, oligostilbene and monoterpene galactoside, have been isolated from the methanolic extract of the fruits of Paeonia emodi. Their structures have been assigned on the basis of spectral analysis including 1D and 2D NMR techniques. In addition
Miklós Poór et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 83, 998-1005 (2016-10-25)
Dietary flavonoids are abundant in the Plant Kingdom and they are extensively studied because of their manifold pharmacological activities. Recent studies highlighted that cell cycle arrest plays a key role in their antiproliferative effect in different tumor cells. However, structure-activity
Yuh-Chiang Shen et al.
European journal of pharmacology, 465(1-2), 171-181 (2003-03-26)
To evaluate the possible mechanisms responsible for the anti-inflammatory effects of baicalin or baicalein, phorbol-12-myristate-13-acetate (PMA)- or N-formyl-methionyl-leucyl-phenylalanine (fMLP)-activated inflammatory responses of peripheral human leukocytes were studied. Both baicalin and baicalein diminished fMLP- or PMA-induced reactive oxygen intermediates production in
Alle zugehörigen Dokumente anzeigen

Artikel

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. At what percentage of DMso baicalein and naringin will be dissolved?

    1 answer

    1. Baicalein and can be soluble in 20mg/ml DMSO. Naringin can be soluble in 10 mg/ml neat DMSO.

      Helpful?

Reviews

No rating value

Active Filters

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.