465089

3,4-Difluorphenylborsäure

≥95%

• Synonym(e): 3,4-Difluorbenzolboronsäure
• Lineare Formel: F₂C₆H₃B(OH)₂
• CAS-Nummer: 168267-41-2
• Molekulargewicht: 157.91
• MDL-Nummer: MFCD00807405
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24870244
• NACRES: NA.22

Eigenschaften

• Assay: ≥95%
• mp (Schmelzpunkt): 305-310 °C (lit.)
• SMILES String: OB(O)c1ccc(F)c(F)c1
• InChI: 1S/C6H5BF2O2/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,10-11H
• InChIKey: RMGYQBHKEWWTOY-UHFFFAOYSA-N

Beschreibung

Anwendung

3,4-Difluorophenylboronic acid can be used as a reactant to prepare:

• Fluorinated biaryl derivatives via Suzuki cross-coupling reaction with aryl and heteroaryl halides.
• Flurodiarylmethanols by reacting with aryl aldehydes using Ni catalyst.
• Conjugated fluorodiazaborinines by treating with diamines via intermolecular dehydration reaction for the detection of explosives.

Reactant involved in:

• Suzuki cross-coupling reactions with aryl and heteroaryl halides
• Oxo directing Liebeskind-Srogl cross-coupling reactions with gem-dihaloolefin-type α-oxo ketene dithioacetals
• Substitution reactions with enyne acetates and carbonates

Sonstige Hinweise

Contains varying amounts of anhydride

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)