376868

2-(2-Aminophenyl)-indol

97%

• Empirische Formel (Hill-System): C₁₄H₁₂N₂
• CAS-Nummer: 32566-01-1
• Molekulargewicht: 208.26
• MDL-Nummer: MFCD00134432
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24863471

Eigenschaften

• Assay: 97%
• mp (Schmelzpunkt): 154-155 °C (lit.)
• SMILES String: Nc1ccccc1-c2cc3ccccc3[nH]2
• InChI: 1S/C14H12N2/c15-12-7-3-2-6-11(12)14-9-10-5-1-4-8-13(10)16-14/h1-9,16H,15H2
• InChIKey: IAKRGXQCKYFJCB-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2-(2-Aminophenyl)indole is an indole derivative. It has been reported as an amination reagent. 2-(2-Aminophenyl)indole undergoes condensation with 4,5-dichloro-1,2,3-dithiazolium chloride (Appel salt) to afford new 6-cyanoindolo[3,2-c]quinoline derivatives, having pharmacological applications.

Anwendung

2-(2-Aminophenyl)indole may be used in the preparation of novel indolo[1,2-c]quinazolines and benzimidazo[1,2-c]quinazolines. It may be used in the synthesis of mono and bis-indolo[1,2-c] quinazolines.

Reactant in:

• cascade reactions of benzopyranylidenemalonates with mono- and dinucleophiles

Reactant for preparation of:

• Mono-, bis-indolo[1,2-c]quinazolines as antimicrobial agents
• Isocryptolepine alkaloid with antimalarial activity
• Cyanoindolo[3,2-c]quinolines and benzimidazo[1,2-c]quinazolines as antitumor agents

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves