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Merck

36070

Sigma-Aldrich

2,6-Dichlor-4-nitro-phenol

98%

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About This Item

Empirische Formel (Hill-System):
C6H3Cl2NO3
CAS-Nummer:
Molekulargewicht:
208.00
Beilstein:
1245045
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:

Assay

≥97.5% (HPLC)
98%

Form

solid

mp (Schmelzpunkt)

123-126 °C (dec.)

Löslichkeit

methanol: soluble 1 g/10 mL, clear, slightly yellow to deep greenish-yellow

SMILES String

Oc1c(Cl)cc(cc1Cl)[N+]([O-])=O

InChI

1S/C6H3Cl2NO3/c7-4-1-3(9(11)12)2-5(8)6(4)10/h1-2,10H

InChIKey

PXSGFTWBZNPNIC-UHFFFAOYSA-N

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Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


Analysenzertifikate (COA)

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S K Hong et al.
Journal of toxicology and environmental health. Part A, 57(1), 47-62 (1999-05-13)
The agricultural fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) is an acute nephrotoxicant in rats. Our previous studies suggested that sulfate conjugation of NDPS metabolites might be a bioactivation step mediating NDPS nephrotoxicity. In this study, effects of substrates and/or inhibitors of sulfation on
Xingxing Diao et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(4), 774-781 (2014-01-29)
3-n-Butylphthalide (NBP) [(±)-3-butyl-1(3H)-isobenzofuranone] is an anti-cerebral-ischemia drug. Moderate hepatotoxicity has been observed in clinical applications. One of the major metabolites, 3-N-acetylcysteine-NBP, has been detected in human urine, indicating the formation of a reactive metabolite. We elucidated the formation mechanism of
L Qi et al.
Apoptosis : an international journal on programmed cell death, 5(4), 379-388 (2001-03-03)
Previous suggestions of CpG-specific apoptotic commitment implied critical epigenetic modulation of housekeeping genes which have canonical CpG islands at 5' promoter regions. Differential housekeeping gene activity however has not been shown. Using a focussed microarray (genechip) of 22 housekeeping genes
K O Wong et al.
Xenobiotica; the fate of foreign compounds in biological systems, 26(1), 17-26 (1996-01-01)
1. Amine N-sulphotransferase (NST) activity with desipramine (DMI) as substrate was assayed in vitro in various areas of the rat brain. Biosynthesis of 3'-phosphoadenosine-5'-phospho35sulphate (PAPS) from sodium 35sulphate and ATP was also measured by coupling it to the sulphation of
H Koster et al.
Biochemical pharmacology, 31(10), 1919-1924 (1982-05-15)
The pharmacokinetics of 2,6-dichloro-4-nitrophenol (DCNP) have been studied in the rat. Upon i.v. injection the plasma decay curve of DCNP showed a rapid distribution phase. After 30 min the plasma concentration reached a value that was constant for at least

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