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126462

Sigma-Aldrich

6,7-Dimethyl-2,3-di(2-pyridyl)chinoxalin

98%

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About This Item

Empirische Formel (Hill-System):
C20H16N4
CAS-Nummer:
6627-38-9
Molekulargewicht:
312.37
EG-Nummer:
229-592-0
MDL-Nummer:
MFCD00006730
UNSPSC-Code:
12352100
PubChem Substanz-ID:
24847727
NACRES:
NA.22

CHF 154.00

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Qualitätsniveau

100

Assay

98%

Form

powder

mp (Schmelzpunkt)

191-193 °C (lit.)

SMILES String

Cc1cc2nc(-c3ccccn3)c(nc2cc1C)-c4ccccn4

InChI

1S/C20H16N4/c1-13-11-17-18(12-14(13)2)24-20(16-8-4-6-10-22-16)19(23-17)15-7-3-5-9-21-15/h3-12H,1-2H3

InChIKey

NACXMBPTPBZQHY-UHFFFAOYSA-N

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Dieser Artikel
213152483370311022
6,7-Dimethyl-2,3-di(2-pyridyl)chinoxalin 98%

126462

6,7-Dimethyl-2,3-di(2-pyridyl)chinoxalin

2,7-Dimethoxynaphthalin 98%

213152

2,7-Dimethoxynaphthalin

2,6-Bis(2-pyridyl)-4(1H)-pyridon 98%

483370

2,6-Bis(2-pyridyl)-4(1H)-pyridon

Di(2-pyridyl)-thioncarbonat 98%

311022

Di(2-pyridyl)-thioncarbonat

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mp

191-193 °C (lit.)

mp

137-139 °C (lit.)

mp

168-170 °C (lit.)

mp

94-98 °C (lit.)

form

powder

form

solid

form

-

form

-

Anwendung

6,7-Dimethyl-2,3-di-(2-pyridyl)quinoxaline has been used as an internal standard to investigate the clinical pharmacokinetics of nelfinavir mesylate, a potent inhibitor of HIV-1 protease[1].

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
STBJ6116
S59885V
S59885
09622HD
08102ED

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E Y Wu et al.
Journal of chromatography. B, Biomedical sciences and applications, 695(2), 373-380 (1997-08-01)
Nelfinavir mesylate, a potent and orally bioavailable inhibitor of HIV-1 protease (Ki=2 nM), has undergone Phase III clinical evaluation in a large population of HIV-positive patients. A high-performance liquid chromatography analytical method was developed to determine the pharmacokinetic parameters of
Salmaan Kanji et al.
Clinical pharmacokinetics, 59(3), 327-334 (2019-09-01)
Sustained low-efficiency dialysis (SLED) is a hybrid form of dialysis that is increasingly used in critically ill patients with kidney injury and hemodynamic instability. Antimicrobial dosing for patients receiving SLED is informed by pharmacokinetic studies that describe the drug clearance.
B Louveau et al.
Biomedical chromatography : BMC, 30(12), 2009-2015 (2016-06-10)
A precise and accurate high-performance liquid chromatography (HPLC) quantification method of rifampicin in human plasma was developed and validated using ultraviolet detection after an automatized solid-phase extraction. The method was validated with respect to selectivity, extraction recovery, linearity, intra- and
Valeria Avataneo et al.
The Journal of antimicrobial chemotherapy, 75(7), 1772-1777 (2020-05-04)
Remdesivir has received significant attention for its potential application in the treatment of COVID-19, caused by SARS-CoV-2. Remdesivir has already been tested for Ebola virus disease treatment and found to have activity against SARS and MERS coronaviruses. The remdesivir core
Sara Baldelli et al.
Therapeutic drug monitoring, 36(6), 739-745 (2014-04-18)
Recently, the European Medicines Agency (EMA) has released new guidelines on the validation of bioanalytical methods. In this work, we compared the analytical performance of 2 high-performance liquid chromatography with tandem mass spectrometry methods designed for the quantification of the

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